Multiple endocrine neoplasia

From Libre Pathology
Revision as of 21:04, 19 March 2011 by Michael (talk | contribs) (ch to caps.)
Jump to navigation Jump to search

Multiple endocrine neoplasia, abbreviated MEN, refers to collection of different genetic abnormalities that lead to endocrine neoplasms.

Simple

MEN 1

Memory device: 3 Ps.

MEN 2A/2B (II/III)

Notes:

  • BOTH have parathyroid adenoma.
  • EACH has one below and one above the diaphragm.

Details

MEN 2A

  • Ganglioneuromatosis of the alimentary tract.[3][4]
    • Extra large nerves in GI tract.

Images:

MEN 2B

References

  1. URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2. Accessed on: 2 September 2010.
  2. Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1162. ISBN 978-1416031215. }}
  3. URL: http://www.ncbi.nlm.nih.gov/omim/162300. Accessed on: 19 November 2010.
  4. Haraguchi M, Kinoshita H, Koori M, et al. (2007). "Multiple rectal carcinoids with diffuse ganglioneuromatosis". World J Surg Oncol 5: 19. doi:10.1186/1477-7819-5-19. PMC 1805501. PMID 17306015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805501/.
  5. Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1160. ISBN 978-1416031215. }}