Difference between revisions of "Multiple endocrine neoplasia"
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'''Multiple endocrine neoplasia''', abbreviated ''MEN'', refers to collection of different genetic abnormalities that lead to endocrine neoplasms. | '''Multiple endocrine neoplasia''', abbreviated ''MEN'', refers to collection of different genetic abnormalities that lead to endocrine neoplasms. | ||
==Simple== | |||
===MEN I=== | ===MEN I=== | ||
* Parathyroid adenoma.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2]. Accessed on: 2 September 2010.</ref> | * Parathyroid adenoma.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2]. Accessed on: 2 September 2010.</ref> | ||
| Line 16: | Line 17: | ||
*BOTH have parathyroid adenoma. | *BOTH have parathyroid adenoma. | ||
*EACH has one below and one above the diaphragm. | *EACH has one below and one above the diaphragm. | ||
==Details== | |||
===MEN IIa=== | |||
*Ganglioneuromatosis of the alimentary tract.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/162300 http://www.ncbi.nlm.nih.gov/omim/162300]. Accessed on: 19 November 2010.</ref><ref name=pmid17306015>{{cite journal |author=Haraguchi M, Kinoshita H, Koori M, ''et al.'' |title=Multiple rectal carcinoids with diffuse ganglioneuromatosis |journal=World J Surg Oncol |volume=5 |issue= |pages=19 |year=2007 |pmid=17306015 |pmc=1805501 |doi=10.1186/1477-7819-5-19 |url=}}</ref> | |||
**Extra large nerves in GI tract. | |||
Image: [http://wjso.com/content/5/1/19/figure/F3 Ganglioneuromatosis - crappy images (wjso.com)]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
Revision as of 17:15, 19 November 2010
Multiple endocrine neoplasia, abbreviated MEN, refers to collection of different genetic abnormalities that lead to endocrine neoplasms.
Simple
MEN I
- Parathyroid adenoma.[1]
- Pancreatic neuroendocrine tumours.
- Pituitary adenoma.
Memory device: 3 Ps.
MEN IIa/IIb (II/III)
- Parathyroid adenoma.
- Medullary thyroid carcinoma.
- Pheochromocytoma.
Notes:
- BOTH have parathyroid adenoma.
- EACH has one below and one above the diaphragm.
Details
MEN IIa
Image: Ganglioneuromatosis - crappy images (wjso.com).
References
- ↑ URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2. Accessed on: 2 September 2010.
- ↑ URL: http://www.ncbi.nlm.nih.gov/omim/162300. Accessed on: 19 November 2010.
- ↑ Haraguchi M, Kinoshita H, Koori M, et al. (2007). "Multiple rectal carcinoids with diffuse ganglioneuromatosis". World J Surg Oncol 5: 19. doi:10.1186/1477-7819-5-19. PMC 1805501. PMID 17306015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805501/.