Morphologic patterns

From Libre Pathology
Revision as of 03:27, 31 October 2015 by Michael (talk | contribs)
Jump to navigation Jump to search

The article deals with morphologic patterns in pathology. It is focused on light microscopy.

The big table of morphology

Name of pattern Meaning DDx (incomplete/abbrev. list) Image
Hobnail basement membrane area < area exposed to luminal surface angiosarcoma, clear cell carcinoma
Angiosarcoma - very high mag. (WC/Nephron)
Storiform spiral appearance or cartwhell pattern[1] solitary fibrous tumour, DFSP, dermatofibroma, UPS
DFSP - very high mag. (WC/Nephron)
Fascicular the long axis of the (spindle) cells are perpendicular to one another in adjacent bundles of cells leiomyoma, leiomyosarcoma
Leiomyosarcoma - very high mag. (WC/Nephron)
Plexiform web-like formation[2] plexiform neurofibroma, MPNST, plexiform lesion of pulmonary hypertension plexiform lesion of Pulm. HTn (flickr.com)
Cribriform pierced with small holes[3] cribriform DCIS, cribriform HGPIN, cribriforming in a tubular adenoma with high-grade dysplasia, endometrioid endometrial carcinoma
Cribriform architecure (ADH) - very high mag. (WC/Nephron)
Solid or Sheeting no architecture - back-to-back cells with no pattern apparent / no spaces between cells solid DCIS, poorly-differentiated malignancy (carcinoma, sarcoma, lymphoma)
Sheeting in a Merkel cell carcinoma - high mag. (WC/Nephron)
Micropapillary nipple like projections without a fibrovascular core (papillary = nipple-like[4]) micropapillary DCIS, micropapillary HGPIN
Micropapillary carcinoma. (WC)
Papillary nipple-like projection with a fibrovascular core papillary thyroid carcinoma
Papillary RCC - high mag. (WC/Nephron)
Flat board-like, does not have a projection above the surface flat DCIS flat DCIS 1 (breastpathology.info),[5] flat DCIS 2 (breastpathology.info)[5]
Herring bone like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right fibrosarcoma, synovial sarcoma, MPNST
MPNST - high mag.(WC/Nephron)
Trabecular or cords trabecula = little beam[6]; quasi-linear arrangement of cells normal liver lobule, Sertoli cell tumour
PTC tall cell variant - high mag. (WC/Nephron)
Nested (nesting) islands of cells with a circular outline neuroendocrine tumours
Neuroendocrine tumour - low mag. (WC/Nephron)
Biphasic / multiple patterns multiple patterns or cell types; e.g. spindle cells and epithelioid cells synovial sarcoma, malignant melanoma, pleomorphic adenoma, angiomyolipoma, chondroid syringoma
DSRCT - high mag. (WC/Nephron)

Patterns

Hobnail pattern

See also

References

  1. Storiform. dictionary.com. URL: http://dictionary.reference.com/browse/storiform. Accessed on: April 24, 2009.
  2. URL: http://www.mondofacto.com/facts/dictionary?plexiform. Accessed on: March 9, 2010.
  3. URL: http://dictionary.reference.com/browse/cribriform. Accessed on: 8 August 2011.
  4. URL: http://dictionary.reference.com/browse/papillary. Accessed on: 8 August 2011.
  5. 5.0 5.1 URL: http://www.breastpathology.info/Sloane/dcis.html. Accessed on: 8 August 2011.
  6. URL: http://dictionary.reference.com/browse/trabecula. Accessed on: 26 December 2010.