Difference between revisions of "Mammary hamartoma"

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#redirect [[Breast_pathology#Mammary_hamartoma]]
'''Mammary hamartoma''', also '''breast hamartoma''', is an uncommon benign pathology of the [[breast]].
 
==General==
*Benign.
*Disordered growth - see ''[[hamartoma]]''.
 
==Gross==
*Well-circumscribed - '''key feature'''.
 
==Microscopic==
Features:<ref name=Ref_BP117>{{Ref BP|117}}</ref>
*Disordered arrangement of ductal and lobular structures.
*Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present.
*Variable features:<ref name=surgpath_stan>URL: [http://surgpathcriteria.stanford.edu/breast/mammhamart/ http://surgpathcriteria.stanford.edu/breast/mammhamart/]. Accessed on: 4 October 2011.</ref>
*#Adipose tissue - predominant.
*#Dense fibrosis tissue - predominant.
*#Cystic glandular dilation.
 
Notes:
*If adipose tissue predominates; it may be labeled ''adenolipoma''.<ref name=surgpath_stan>URL: [http://surgpathcriteria.stanford.edu/breast/mammhamart/ http://surgpathcriteria.stanford.edu/breast/mammhamart/]. Accessed on: 4 October 2011.</ref>
 
DDx:
*[[Fibroadenoma]] - may have adipose tissue.
*[[Phyllodes tumour]] - may have adipose tissue.
*[[Pseudoangiomatous stromal hyperplasia]].
*[[Fibrocystic changes]].
 
===Images===
*[http://www.breastpathology.info/sub-pages-iotw/2008/18.html Mammary hamartoma (breastpathology.info)].
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/figure/f2/ Mammary hamartoma (nih.gov)].<ref name=pmid12461066>{{Cite journal  | last1 = Tse | first1 = GM. | last2 = Law | first2 = BK. | last3 = Ma | first3 = TK. | last4 = Chan | first4 = AB. | last5 = Pang | first5 = LM. | last6 = Chu | first6 = WC. | last7 = Cheung | first7 = HS. | title = Hamartoma of the breast: a clinicopathological review. | journal = J Clin Pathol | volume = 55 | issue = 12 | pages = 951-4 | month = Dec | year = 2002 | doi =  | PMID = 12461066 | PMC = 1769817 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/}}</ref>
 
==IHC==
*None - it's a [[H&E]] diagnosis.
 
==See also==
*[[Breast pathology]].
*[[Hamartoma]].
 
==References==
{{Reflist|2}}
 
[[Category:Diagnosis]]
[[Category:Breast pathology]]

Latest revision as of 04:32, 16 February 2014

Mammary hamartoma, also breast hamartoma, is an uncommon benign pathology of the breast.

General

Gross

  • Well-circumscribed - key feature.

Microscopic

Features:[1]

  • Disordered arrangement of ductal and lobular structures.
  • Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present.
  • Variable features:[2]
    1. Adipose tissue - predominant.
    2. Dense fibrosis tissue - predominant.
    3. Cystic glandular dilation.

Notes:

  • If adipose tissue predominates; it may be labeled adenolipoma.[2]

DDx:

Images

IHC

  • None - it's a H&E diagnosis.

See also

References

  1. O'Malley, Frances P.; Pinder, Sarah E. (2006). Breast Pathology: A Volume in Foundations in Diagnostic Pathology series (1st ed.). Churchill Livingstone. pp. 117. ISBN 978-0443066801.
  2. 2.0 2.1 URL: http://surgpathcriteria.stanford.edu/breast/mammhamart/. Accessed on: 4 October 2011.
  3. Tse, GM.; Law, BK.; Ma, TK.; Chan, AB.; Pang, LM.; Chu, WC.; Cheung, HS. (Dec 2002). "Hamartoma of the breast: a clinicopathological review.". J Clin Pathol 55 (12): 951-4. PMC 1769817. PMID 12461066. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/.