MOC31
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MOC31 is an immunostain. The antibody is directed against the epithelial cell adhesion molecule (Ep-CAM, TACSTD1).[1]
Negative
- Hepatocellular carcinoma.[2]
- Malignant epithelioid mesothelioma - usually negative.[3]
Positive
- Cholangiocarcinoma.[2]
- Liver metastases.[2]
- Lung adenocarcinoma.[3]
- Invasive ductal carcinoma of the breast.[1]
- Invasive lobular carcinoma.[1]
See also
References
- ↑ 1.0 1.1 1.2 Pai, RK.; West, RB. (May 2009). "MOC-31 exhibits superior reactivity compared with Ber-EP4 in invasive lobular and ductal carcinoma of the breast: a tissue microarray study.". Appl Immunohistochem Mol Morphol 17 (3): 202-6. PMID 19391212.
- ↑ 2.0 2.1 2.2 Proca, DM.; Niemann, TH.; Porcell, AI.; DeYoung, BR. (Jun 2000). "MOC31 immunoreactivity in primary and metastatic carcinoma of the liver. Report of findings and review of other utilized markers.". Appl Immunohistochem Mol Morphol 8 (2): 120-5. PMID 10937059.
- ↑ 3.0 3.1 Ordóñez, NG. (Feb 1998). "Value of the MOC-31 monoclonal antibody in differentiating epithelial pleural mesothelioma from lung adenocarcinoma.". Hum Pathol 29 (2): 166-9. PMID 9490276.