Long-term epilepsy associated tumor
Long-term epilepsy associated tumors, abbreviated LEAT is an umbrella term for rare tumor entities in patients that do not match current WHO diagnostic criteria.
General
- Closely associated with Ganglioglioma and DNT.
Examples
- Papillary glioneuronal tumor [1]
- Angiocentric glioma [2]
- Isomorphic diffuse glioma [3]
- Multinodular and vacuolating neuronal tumor of the cerebrum [4]
- Polymorphous low grade tumor of the young [5]
Criteria
- Seizures <18 years.
- Temporal lobe location.
- Mostly benign appearance (as in WHO grade I).
See also
References
- ↑ "Papillary glioneuronal tumour: a review of the literature with two illustrative cases". Br J Neurosurg 27 (3): 401–4. June 2013. doi:10.3109/02688697.2012.741735. PMID 23173837.
- ↑ "Rare glial tumors". Handb Clin Neurol 134: 399–415. 2016. doi:10.1016/B978-0-12-802997-8.00024-4. PMID 26948368.
- ↑ "Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course". Acta Neuropathol 139 (1): 193–209. January 2020. doi:10.1007/s00401-019-02078-w. PMC 7477753. PMID 31563982. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477753/.
- ↑ "Multinodular and vacuolating neuronal tumor of the cerebrum: Two cases and review of the literature". Clin Neurol Neurosurg 197: 106149. October 2020. doi:10.1016/j.clineuro.2020.106149. PMID 32979644.
- ↑ "Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway". Acta Neuropathol 133 (3): 417–429. March 2017. doi:10.1007/s00401-016-1639-9. PMC 5325850. PMID 27812792. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325850/.