Difference between revisions of "Laryngeal carcinoma"
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'''Laryngeal carcinoma''' is a subset of [[head and neck pathology]]. | '''Laryngeal carcinoma''' is a subset of [[head and neck pathology]]. | ||
== | =Normal histology= | ||
The normal histology is dependent on the site.<ref name=pmid12530572>{{Cite journal | last1 = Koren | first1 = R. | last2 = Kristt | first2 = D. | last3 = Shvero | first3 = J. | last4 = Yaniv | first4 = E. | last5 = Dekel | first5 = Y. | last6 = Gal | first6 = R. | title = The spectrum of laryngeal neoplasia: the pathologist's view. | journal = Pathol Res Pract | volume = 198 | issue = 11 | pages = 709-15 | month = | year = 2002 | doi = | PMID = 12530572 }}</ref> | |||
=Pathology= | |||
==Laryngeal squamous cell carcinoma== | |||
===General=== | |||
*95% of laryngeal carcinomas.<ref name=Ref_PCPBoD8_396>{{Ref PCPBoD8|396}}</ref> | |||
Risk factors:<ref name=Ref_PCPBoD8_396>{{Ref PCPBoD8|396}}</ref> | |||
# [[Smoking]]. | |||
# [[Alcohol]]. | |||
Note: | |||
*Asbestos exposure is also reported to be associated.<Ref name=pmid24351898>{{Cite journal | last1 = Offermans | first1 = NS. | last2 = Vermeulen | first2 = R. | last3 = Burdorf | first3 = A. | last4 = Goldbohm | first4 = RA. | last5 = Kauppinen | first5 = T. | last6 = Kromhout | first6 = H. | last7 = van den Brandt | first7 = PA. | title = Occupational asbestos exposure and risk of pleural mesothelioma, lung cancer, and laryngeal cancer in the prospective Netherlands cohort study. | journal = J Occup Environ Med | volume = 56 | issue = 1 | pages = 6-19 | month = Jan | year = 2014 | doi = 10.1097/JOM.0000000000000060 | PMID = 24351898 }}</ref> | |||
====Carinoma - subclassification by site==== | |||
It is generally divided the following way:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Larynx_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Larynx_11protocol.pdf]. Accessed on: 2 May 2012.</ref> | It is generally divided the following way:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Larynx_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Larynx_11protocol.pdf]. Accessed on: 2 May 2012.</ref> | ||
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Features:<ref name=Ref_WMSP24>{{Ref WMSP|24}}</ref><ref>URL: [http://www.health.am/cr/more/statistics-and-prognosis-for-cancer-of-the-larynx/ http://www.health.am/cr/more/statistics-and-prognosis-for-cancer-of-the-larynx/]. Accessed on: 2 May 2012.</ref> | |||
*Prevalence - glottis > supraglottis > subglottis. | |||
*Glottic carcinoma tends to present earlier (as it affects phonation) and, therefore, has a better prognosis. | |||
===Microscopic=== | |||
:See [[squamous cell carcinoma]]. | |||
===Sign out=== | |||
<pre> | |||
LEFT FALSE VOCAL CORD, BIOPSY: | |||
- INVASIVE SQUAMOUS CELL CARCINOMA, MODERATELY DIFFERENTIATED, NONKERATINIZING, | |||
WITH LYMPHOVASCULAR INVASION. | |||
COMMENT: | |||
The presence of invasive squamous cell carcinoma is confirmed by a second pathologist. | |||
</pre> | |||
=See also= | |||
*[[Head and neck pathology]]. | *[[Head and neck pathology]]. | ||
*[[Squamous cell carcinoma]]. | *[[Squamous cell carcinoma]]. | ||
*[[Laryngectomy]]. | |||
=References= | |||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Head and neck pathology]] | [[Category:Head and neck pathology]] | ||
Latest revision as of 14:45, 13 November 2020
Laryngeal carcinoma is a subset of head and neck pathology.
Normal histology
The normal histology is dependent on the site.[1]
Pathology
Laryngeal squamous cell carcinoma
General
- 95% of laryngeal carcinomas.[2]
Risk factors:[2]
Note:
- Asbestos exposure is also reported to be associated.[3]
Carinoma - subclassification by site
It is generally divided the following way:[4]
| Laryngeal cancer | |||||||||||||||||||||||||||||||||
| Supraglottis | Glottis | Subglottis | |||||||||||||||||||||||||||||||
- Prevalence - glottis > supraglottis > subglottis.
- Glottic carcinoma tends to present earlier (as it affects phonation) and, therefore, has a better prognosis.
Microscopic
Sign out
LEFT FALSE VOCAL CORD, BIOPSY: - INVASIVE SQUAMOUS CELL CARCINOMA, MODERATELY DIFFERENTIATED, NONKERATINIZING, WITH LYMPHOVASCULAR INVASION. COMMENT: The presence of invasive squamous cell carcinoma is confirmed by a second pathologist.
See also
References
- ↑ Koren, R.; Kristt, D.; Shvero, J.; Yaniv, E.; Dekel, Y.; Gal, R. (2002). "The spectrum of laryngeal neoplasia: the pathologist's view.". Pathol Res Pract 198 (11): 709-15. PMID 12530572.
- ↑ 2.0 2.1 Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 396. ISBN 978-1416054542.
- ↑ Offermans, NS.; Vermeulen, R.; Burdorf, A.; Goldbohm, RA.; Kauppinen, T.; Kromhout, H.; van den Brandt, PA. (Jan 2014). "Occupational asbestos exposure and risk of pleural mesothelioma, lung cancer, and laryngeal cancer in the prospective Netherlands cohort study.". J Occup Environ Med 56 (1): 6-19. doi:10.1097/JOM.0000000000000060. PMID 24351898.
- ↑ URL: http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Larynx_11protocol.pdf. Accessed on: 2 May 2012.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 24. ISBN 978-0781765275.
- ↑ URL: http://www.health.am/cr/more/statistics-and-prognosis-for-cancer-of-the-larynx/. Accessed on: 2 May 2012.