Kidney cytopathology
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Kidney cytopathology, also renal cytopathology, is uncommonly done.
Kidney cytology and renal cytology redirect here.
Angiomyolipoma
Main article: Angiomyolipoma
General
- May be associated with tuberous sclerosis.
Cytology
Features:
- Blood vessels.
- Fat - usu. scant.
- Muscle - ovoid, bent cigar-shaped nuclei.
Renal oncocytoma
Main article: Renal oncocytoma
Cytology
Features:[1]
- Moderate granular cytoplasm.
- Distinct cell borders.
- Round nuclei.
Oncocytoma vs chromophobe RCC:[1]
- ChRCC:
- Thicker cell borders.
- Perinuclear clearing/quasi koilocytic appearance.
Image:
Clear cell renal cell carcinoma
Main article: Clear cell renal cell carcinoma
Cytology
Features - classically:
- Prominent nucleoli.
- Abundant vacuolated, delicate cytoplasm.
- Small blood vessels (chicken-wire vasculature).
Note:
- Cytoplasm not clear.
DDx:
- Xanthogranulomatous pyelonephritis - histiocytes, typically single cells - may be in small groups.
Images:
Chromophobe renal cell carcinoma
Main article: Chromophobe renal cell carcinoma
Cytology
Features:
- Thick appearing cell membrane - vegetable matter-like appearance.
Papillary renal cell carcinoma
Main article: Papillary renal cell carcinoma
Cytology
Features:
- Papillary structures - typically have a smooth contour.
- Contain foamy macrophages.
- Tumour cells have small nucleoli +/- nuclear grooves.
- +/-Psammoma bodies.
See also
References
- ↑ 1.0 1.1 Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 683. ISBN 978-1416025887.
- ↑ 2.0 2.1 URL: http://moon.ouhsc.edu/kfung/jty1/CytoLearn/CytoQuiz/CQ-021-040/CQ-025-M.htm. Accessed on: 9 April 2012.