Intraoperative consultation

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Intraoperative consultation, also quick section and frozen section, is when a surgeon requests an opinion during an operation so that they can appropriately manage a patient. It is abbreviated IC. Frozen section is often abbreviated FS.

Why intraoperative consultations are done

Reasons why IC are done:[1]

  1. Determine diagnosis & appropriate extent of operation ~ 50%.
  2. Margin status ~ 15%.
  3. Triage tissue ~ 10%.
  4. Inform family ~ 8%. †
  5. Sufficient tissue? ~ 8%.
  6. Treatment planning ~ 3%.

Note:

  • † Some don't consider this a good reason for an IC.[2]

Why intraoperative consultations may be refused

  • Tissue is the issue - not enough of it.
  • Infectious case and no back-up cryostat.
  • Management - it won't make a difference.
    • Diagnosis won't make a difference.
    • Cannot make the diagnosis.
      • Bone tumours.

Frozen section permanent section concordance

Categories by the Association of Directors of Anatomic and Surgical Pathology (ADASP):[3]

  • Agreement
  • Deferral - appropriate.
  • Deferral – inappropriate
    • Recommendation <=10% threshold.
  • Disagreement – Minor.
  • Disagreement – Major.
    • Recommendation <=3% threshold.

Common specimens

Table of common FS specimens

Specimen Indication Subspecialty
Pelvic mass diagnosis gynecologic pathology
Ovarian mass diagnosis gynecologic pathology
Uterine mass diagnosis gynecologic pathology
Sentinel lymph node staging in vulvar melanoma gynecologic pathology
Squamous cell carcinoma margins head and neck pathology
Whipple procedure margins gastrointestinal pathology
Liver resection (usu. metastatic disease) margins gastrointestinal pathology
Lower anterior resection distal margin gastrointestinal pathology
Cystectomy/cystoprostatectomy ureteral margins genitourinary pathology
Pneumonectomy (usu. cancer) bronchus margin, lymph nodes for staging pulmonary pathology
Brain tumour diagnosis neuropathology
Spinal tumour diagnosis neuropathology
Thyroid nodule diagnosis thyroid pathology
Prosthetic joint query prosthetic joint infection joint pathology

List of specimens

Gynecologic

  • Pelvic mass - diagnosis (benign/borderline/malignant).
  • Ovarian mass - diagnosis (benign/borderline/malignant).
  • Uterine mass - diagnosis (benign/borderline/malignant).
  • Sentinel lymph node - staging.

Head and neck

  • Squamous cell carcinoma - margins.

Gastrointestinal tract

  • Whipple procedure - margins.
  • Liver resection - margins.
  • Lower anterior resection - distal margin.

Genitourinary tract

  • Cystectomy - ureteral margins.

Pulmonary

  • Pneumonectomy:

Neurologic

Thyroid gland

  • Thyroid nodule - diagnosis.

Prosthetic joint

Surgeon-pathologist dialog

It should include:

  1. Identification:
    • Pathology is calling - Dr. X is speaking.
    • Patient identifiers - full name.
    • Part(s) submitted.
  2. Diagnosis.
  3. Repeat of diagnosis from surgeon.
  4. Additional requests?

Specific specimens - checklists

Ovarian mass

Covers adnexal mass and pelvic mass.

General:

  • Specimen integrity: fragmented/intact/ruptured.
  • Dimensions: ___ x ___ x ___ cm.
  • Mass: ___ grams.
  • Surface involvement: absent/present.
  • Consistency: solid/cystic/solid and cystic.

Cystic:

  • Type: unilocular, multilocular.
  • Cyst content: mucinous/serous/hemorrhagic/purulent/chylous/other. ‡
  • Papillary excrescences: absent/present.
  • Necrosis: absent/present.
  • Hair: absent/present.

Sections:

  • Sample morphologically distinct areas - esp. solid areas, papillary excrescences.

Notes:

  • ‡ Mucinous versus serous:
    • Serous: low viscosity (flows threw the grate typically seen at the bottom of sinks with ease[4]).
    • Mucinous: high viscosity (jello-like consistency).

See also

References

  1. Zarbo, RJ.; Schmidt, WA.; Bachner, P.; Howanitz, PJ.; Meier, FA.; Schifman, RB.; Boone, DJ.; Herron, RM. (Jan 1996). "Indications and immediate patient outcomes of pathology intraoperative consultations. College of American Pathologists/Centers for Disease Control and Prevention Outcomes Working Group Study.". Arch Pathol Lab Med 120 (1): 19-25. PMID 8554440.
  2. Taxy, J.; Husain, A; Montag, A. (2009). Biopsy Interpretation: The Frozen Section (1st ed.). Lippincott Williams & Wilkins. pp. 5. ISBN 978-0781767798.
  3. URL: http://www.adasp.org/papers/position/QualityAssurance.htm. Accessed on: 2 March 2012.
  4. Taxy, J.; Husain, A; Montag, A. (2009). Biopsy Interpretation: The Frozen Section (1st ed.). Lippincott Williams & Wilkins. pp. 33. ISBN 978-0781767798.