Difference between revisions of "Hepatocyte nuclear factor-1beta"

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==Positive==
==Positive==
*[[Clear cell carcinoma of the ovary]].
*[[Clear cell carcinoma of the ovary]].
*Renal cell carcinoma<ref name=pmid32150988>{{cite journal |authors=Kim M, Joo JW, Lee SJ, Cho YA, Park CK, Cho NH |title=Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes |journal=Cancers (Basel) |volume=12 |issue=3 |pages= |date=March 2020 |pmid=32150988 |pmc=7139472 |doi=10.3390/cancers12030602 |url=}}</ref> - including [[clear cell renal cell carcinoma]].<ref name=pmid26574638>{{cite journal |authors=Hanley KZ, Cohen C, Osunkoya AO |title=Hepatocyte Nuclear Factor-1β Expression in Clear Cell Renal Cell Carcinoma and Urothelial Carcinoma With Clear Cell Features: A Potential Diagnostic Pitfall |journal=Appl. Immunohistochem. Mol. Morphol. |volume=25 |issue=2 |pages=134–138 |date=February 2017 |pmid=26574638 |doi=10.1097/PAI.0000000000000279 |url=}}</ref>
*[[Renal cell carcinoma]]<ref name=pmid32150988>{{cite journal |authors=Kim M, Joo JW, Lee SJ, Cho YA, Park CK, Cho NH |title=Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes |journal=Cancers (Basel) |volume=12 |issue=3 |pages= |date=March 2020 |pmid=32150988 |pmc=7139472 |doi=10.3390/cancers12030602 |url=}}</ref> - including [[clear cell renal cell carcinoma]].<ref name=pmid26574638>{{cite journal |authors=Hanley KZ, Cohen C, Osunkoya AO |title=Hepatocyte Nuclear Factor-1β Expression in Clear Cell Renal Cell Carcinoma and Urothelial Carcinoma With Clear Cell Features: A Potential Diagnostic Pitfall |journal=Appl. Immunohistochem. Mol. Morphol. |volume=25 |issue=2 |pages=134–138 |date=February 2017 |pmid=26574638 |doi=10.1097/PAI.0000000000000279 |url=}}</ref>


Note:
Note:

Revision as of 17:45, 30 March 2021

Hepatocyte nuclear factor-1beta, abbreviated HNF-1beta and HNF-1β, is an immunostain that marks clear cell carcinoma of the ovary.

Positive

Note:

  • CA-125, RCCma, and CD10 can help distinguish clear cell renal cell carcinoma and Müllerian cell cell tumours.[3]

Negative

References

  1. Kim M, Joo JW, Lee SJ, Cho YA, Park CK, Cho NH (March 2020). "Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes". Cancers (Basel) 12 (3). doi:10.3390/cancers12030602. PMC 7139472. PMID 32150988. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139472/.
  2. Hanley KZ, Cohen C, Osunkoya AO (February 2017). "Hepatocyte Nuclear Factor-1β Expression in Clear Cell Renal Cell Carcinoma and Urothelial Carcinoma With Clear Cell Features: A Potential Diagnostic Pitfall". Appl. Immunohistochem. Mol. Morphol. 25 (2): 134–138. doi:10.1097/PAI.0000000000000279. PMID 26574638.
  3. Mentrikoski MJ, Wendroth SM, Wick MR (October 2014). "Immunohistochemical distinction of renal cell carcinoma from other carcinomas with clear-cell histomorphology: utility of CD10 and CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin". Appl Immunohistochem Mol Morphol 22 (9): 635–41. doi:10.1097/PAI.0000000000000004. PMID 25279712.