HELLP syndrome
Jump to navigation
Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
HELLP syndrome is an uncommon pathology of pregnancy that is diagnosed clinically and is defined by hemolysis, elevated liver enzymes and low platelets.
General
- Diagnosed clinically.
- Pathologically not the same as severe preclampsia.[1]
Definition:
- H = hemolysis.
- EL = elevated liver enzymes.
- LP = low platelets.
Microscopic
Features:[2]
- Thrombotic microangiopathic vasculopathy.
- In essence: severe hypertrophic decidual vasculopathy. (???)
See also
References
- ↑ Vinnars MT, Wijnaendts LC, Westgren M, Bolte AC, Papadogiannakis N, Nasiell J (May 2008). "Severe preeclampsia with and without HELLP differ with regard to placental pathology". Hypertension 51 (5): 1295–9. doi:10.1161/HYPERTENSIONAHA.107.104844. PMID 18362224.
- ↑ Ornstein MH, Rand JH (July 1994). "An association between refractory HELLP syndrome and antiphospholipid antibodies during pregnancy; a report of 2 cases". J. Rheumatol. 21 (7): 1360–4. PMID 7966086.