Fibrous pseudotumour of the paratesticular region

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Fibrous pseudotumour of the paratesticular region
Diagnosis in short

Paratesticular fibrous pseudotumour. H&E stain.
LM spindle cells with moderate eosinophilic cytoplasm and indistinct cellular borders, no significant nuclear atypia
LM DDx leiomyoma, fibroma of the tunics, fibromatosis, solitary fibrous tumour, inflammatory pseudotumour
IHC CD34 +ve/-ve, S-100 -ve, desmin -ve, keratins -ve
Site paratesticular region
Prevalence very rare
Prognosis good
Clin. DDx other paratesticular lesions and testicular lesions
Treatment surgical excision to exclude serious pathology

Fibrous pseudotumour of the paratesticular region is a very rare tumour of the paratesticular region.[1]

General

  • May be associated with the epididymis or tunica vaginalis of the testis.[2]
    • Uncommonly associated with the epididymis (<10% of tumours[3]).

Microscopic

Features:[2]

  • Spindle cells with:
    • Moderate eosinophilic cytoplasm.
    • Indistinct cellular borders.

DDx:[2]

Images

  • PFP - very low mag.

  • PFP - low mag.

  • PFP - intermed. mag.

  • PFP - intermed. mag.

  • PFP - high mag.

IHC

Features:[4]

  • CD34 +ve/-ve.
  • S-100 -ve.
  • Desmin -ve.
  • Keratin -ve.

See also

References

  1. ↑ Bharti, JN.; Dey, B.; Mittal, A.; Arora, P. (Dec 2013). "A case of fibrous pseudotumor of the paratesticular region.". World J Mens Health 31 (3): 262-4. doi:10.5534/wjmh.2013.31.3.262. PMID 24459661.
  2. ↑ 2.0 2.1 2.2 Zhang, Z.; Yang, J.; Li, M.; Cai, W.; Liu, Q.; Wang, T.; Guo, X.; Wang, S. et al. (Mar 2014). "Paratesticular fibrous pseudotumor: a report of five cases and literature review.". Front Med. doi:10.1007/s11684-014-0325-3. PMID 24627288.
  3. ↑ Tobias-machado, M.; Corrêa Lopes Neto, A.; Heloisa Simardi, L.; Borrelli, M.; Wroclawski, ER. (Oct 2000). "Fibrous pseudotumor of tunica vaginalis and epididymis.". Urology 56 (4): 670-2. PMID 11018636.
  4. ↑ Jones, MA.; Young, RH.; Scully, RE. (Mar 1997). "Benign fibromatous tumors of the testis and paratesticular region: a report of 9 cases with a proposed classification of fibromatous tumors and tumor-like lesions.". Am J Surg Pathol 21 (3): 296-305. PMID 9060599.
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