Fibromatoses

From Libre Pathology
Revision as of 20:29, 30 January 2013 by Michael (talk | contribs) (→‎Microscopic: more)
Jump to navigation Jump to search

Fibromatoses are a group of benign stromal lesions that may be seen in pediatric pathology and may or may not be associated with syndromes.

Syndromes associated with fibromatoses

Types

Superficial

Deep

Gross

  • Firm.
  • Infiltrative borders.

Image:

Microscopic

Features:

  • Bland spindle cells - typically in fascicles.
    • Pale eosinophilic cytoplasm.[2]
  • Small thin blood vessels that are parallel to one another.
    • Nuclei of blood vessels are typically darker staining than those of the lesion.

DDx:

Images:

IHC

Image:

See also

References

  1. Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1092. ISBN 978-1416031215.
  2. URL: http://www.histopathology-india.net/Fibromatosis.htm. Accessed on: 18 September 2012.
  3. Murphey, MD.; Ruble, CM.; Tyszko, SM.; Zbojniewicz, AM.; Potter, BK.; Miettinen, M. (Nov 2009). "From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation.". Radiographics 29 (7): 2143-73. doi:10.1148/rg.297095138. PMID 19926768.

External links