Ferruginous body
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Ferruginous body is a histopathologic finding in lung pathology that strongly suggests exposure to asbestos.
General
- Uncommon finding.
- Strongly suggestive of asbestos exposure.
Conditions associated with asbestos exposure (mnemonic PALM):[1]
Microscopic
Features:
- Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
- Black/brown crystal-like appearance.
DDx:
- Dirt - especially on H&E.
Images
Cytology
Stains
- Prussian blue stain +ve.
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Comment: No cell block is available for further work-up, e.g. iron staining. The findings herein should be correlated with imaging and the clinical history. Ferruginous bodies are associated asbestos exposure.
See also
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 375. ISBN 978-1416054542.