Exaggerated placental site
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Exaggerated placental site, abbreviated EPS, is an uncommon benign pathology that is a gestational trophoblastic disease.
It was previously known as syncytial endometritis.[1][2]
General
- Benign.
Definition:
- "Increased number" of implantation-site intermediate trophoblastic cells.
Note:
- Used to go by a terrible old term: syncytial endometritis:[3]
- Not syncytial -- mostly.
- Not inflammatory.
Microscopic
Features:[3]
- Intermediate trophoblast:
- Abundant (eosinophilic) cytoplasm.
- Usu. adjacent to:
- Chorionic villi.
- Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders.
- No mitotic activity.
- Ectatic blood vessels.
DDx:
- PSTT.
Image
IHC
See also
References
- ↑ URL: http://www.webpathology.com/image.asp?case=565&n=7. Accessed on: 22 May 2014.
- ↑ 2.0 2.1 Heyderman E, Gibbons AR, Rosen SW (March 1981). "Immunoperoxidase localisation of human placental lactogen: a marker for the placental origin of the giant cells in 'syncytial endometritis' of pregnancy". J. Clin. Pathol. 34 (3): 303–7. PMC 1146481. PMID 7014653. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1146481/.
- ↑ 3.0 3.1 URL: http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf. Accessed on: 15 August 2011.
- ↑ 4.0 4.1 Shen DH, Liao XY, Liu YL, Wang H, Yu YZ (October 2004). "[Clinicopathological study of intermediate trophoblastic non-tumor lesions: exaggerated placental site and placental site nodule]" (in Chinese). Zhonghua Bing Li Xue Za Zhi 33 (5): 441–4. PMID 15498215.