Difference between revisions of "Epithelioid cell lesions"

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'''Epithelioid cell lesions''' are very common in pathology.
[[Image:Epithelioid sarcoma - cropped - very high mag.jpg|thumb|right|250px|An tumour with an epithelioid morphology ([[epithelioid sarcoma]]). [[H&E stain]].]]
'''Epithelioid cell lesions''' are very common in pathology. Malignant epithelioid lesions are most often carcinomas... but may be a large number different tumours.


Malignant epithelioid lesions are usually a carcinoma.
==Classification==
Broadly, epithelioid lesions are split into:
*[[Small round cell tumours]].
*[[Large epithelioid tumours]].


A short differential diagnosis:
==General differential diagnosis==
A short DDx:
*Carcinoma (primary and metastatic).
*Carcinoma (primary and metastatic).
*[[Malignant melanoma]].
*[[Malignant melanoma]].
*Sarcoma.
*Sarcoma.


==Epithelioid sarcomas==
===Epithelioid sarcomas===
All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref>
All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref>
*[[Epithelioid sarcoma]].
*[[Epithelioid sarcoma]].
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*[[Synovial sarcoma]], primitive round cell type.
*[[Synovial sarcoma]], primitive round cell type.
*Sarcomas in the ''[[small round cell tumours]]'' group, e.g. [[Ewing sarcoma]].
*Sarcomas in the ''[[small round cell tumours]]'' group, e.g. [[Ewing sarcoma]].
Note:
*An exhaustive [[DDx]] is found in ''[[large epithelioid tumours]]'' and ''[[small round cell tumours]]''.


==See also==
==See also==
*[[Spindle cell lesions]].
*[[Spindle cell lesions]].
*[[Basics]].
*[[Pleomorphic tumours]].
*[[Large epithelioid tumours]].


==References==
==References==

Latest revision as of 06:55, 1 November 2014

An tumour with an epithelioid morphology (epithelioid sarcoma). H&E stain.

Epithelioid cell lesions are very common in pathology. Malignant epithelioid lesions are most often carcinomas... but may be a large number different tumours.

Classification

Broadly, epithelioid lesions are split into:

General differential diagnosis

A short DDx:

Epithelioid sarcomas

All rules are made to be broken... some epithelioid lesions are sarcomas:[1]

Others:

Note:

See also

References

  1. Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S (August 2009). "Epithelioid soft tissue tumors". Semin. Oncol. 36 (4): 347–57. doi:10.1053/j.seminoncol.2009.06.005. PMID 19664495.