Endosalpingiosis
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Endosalpingiosis | |
---|---|
Diagnosis in short | |
Endosalpingiosis. H&E stain. | |
| |
LM | cystic lesion with ciliated epithelium surrounded by fibrous stroma, psammoma bodies |
LM DDx | endometriosis, serous carcinoma, adenocarcinoma, peritoneal inclusion cyst |
IHC | CK7 +ve, WT-1 +ve, CA125 +ve |
Site | peritoneum, omentum, lymph node (rare) |
| |
Clinical history | may be associated with endometriosis; incidental finding |
Prognosis | benign |
Endosalpingiosis is a benign entity that can be confused for cancer.
General
- Benign entity that may lead to a misdiagnosis of adenocarcinoma[1] or serous carcinoma.
- The clinical significance of endosalpingiosis is not definitively settled; opinions differ on whether it is:
Microscopic
Features:[4]
- Cystic lesions with:
- Ciliated (tubal type) epithelium, without endometrial stroma.
- Endosalpingiosis is surrounded by fibrous stroma; tubal type epithelial surrounded by ovarian stroma is a variant of endometriosis.
- Ciliated (tubal type) epithelium, without endometrial stroma.
- Associated with psammoma bodies.[5]
Notes:
- Not associated with hemorrhage.[6]
- In a lymph node, endosalpingiosis may be misinterpreted as a metastasis![7]
DDx:[8]
- Serous carcinoma.
- Peritoneal inclusion cyst.
- Adenocarcinoma.
- Papillary carcinoma.
Images
IHC
Features:[9]
- CK7 +ve.
- WT-1 +ve.
- CA125 +ve.
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OVARIAN FOSSA, RIGHT, BIOPSY: - ENDOMETRIOSIS. - ENDOSALPINGIOSIS. - FIBROADIPOSE TISSUE PARTIALLY COVERED BY MESOTHELIUM.
See also
References
- ↑ Lin O (May 2009). "Challenges in the interpretation of peritoneal cytologic specimens". Arch. Pathol. Lab. Med. 133 (5): 739–42. PMID 19415948.
- ↑ deHoop, TA.; Mira, J.; Thomas, MA. (Oct 1997). "Endosalpingiosis and chronic pelvic pain.". J Reprod Med 42 (10): 613-6. PMID 9350013.
- ↑ Heinig, J.; Gottschalk, I.; Cirkel, U.; Diallo, R. (Jun 2002). "Endosalpingiosis-an underestimated cause of chronic pelvic pain or an accidental finding? A retrospective study of 16 cases.". Eur J Obstet Gynecol Reprod Biol 103 (1): 75-8. PMID 12039470.
- ↑ URL: http://radiographics.rsna.org/content/29/2/347.full. Accessed on: 27 May 2010.
- ↑ Hallman KB, Nahhas WA, Connelly PJ (September 1991). "Endosalpingiosis as a source of psammoma bodies in a Papanicolaou smear. A case report". J Reprod Med 36 (9): 675–8. PMID 1774734.
- ↑ URL: http://radiographics.rsna.org/content/29/2/347.full. Accessed on: 27 May 2010.
- ↑ Corben, AD.; Nehhozina, T.; Garg, K.; Vallejo, CE.; Brogi, E. (Aug 2010). "Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma.". Am J Surg Pathol 34 (8): 1211-6. doi:10.1097/PAS.0b013e3181e5e03e. PMID 20631604.
- ↑ Rosenberg, P.; Nappi, L.; Santoro, A.; Bufo, P.; Greco, P. (Mar 2011). "Pelvic mass-like florid cystic endosalpingiosis of the uterus: a case report and a review of literature.". Arch Gynecol Obstet 283 (3): 519-23. doi:10.1007/s00404-010-1700-1. PMID 20931212.
- ↑ Stolnicu S, Preda O, Kinga S, et al. (2011). "Florid, papillary endosalpingiosis of the axillary lymph nodes". Breast J 17 (3): 268–72. doi:10.1111/j.1524-4741.2011.01081.x. PMID 21477174.