Emperipolesis
Jump to navigation
Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Emperipolesis is an intact cell within another cell. The term is derived from em (inside), peri (around), and polemai (is wander about).
General
- Nonspecific finding seen in a number of conditions.
It is seen in:
- Rosai-Dorfman disease.
- Megakaryocytes.[1]
- Autoimmune hepatitis.
Microscopic
Features:
- Intact cell (e.g. lymphocyte, neutrophil) within a macrophage.
- Engulfed cell usually has a halo around it.
DDx:
- Cell overlap.
- Hemophagocytosis.
Images
Emperipolesis in Rosai-Dorfman disease. S100 immunostain.
Megakaryocyte containing a neutrophil. May-Grünwald Giemsa stain.
