Difference between revisions of "Crizotinib"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
'''Crizotinib''' a drug used to treat lung cancer. Its' trade name is ''Xalkori'' (Pfizer).<ref>URL: [https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/crizotinib https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/crizotinib]. Accessed on: November 8, 2018.</ref> | '''Crizotinib''' a drug used to treat lung cancer. Its' trade name is ''Xalkori'' (Pfizer).<ref>URL: [https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/crizotinib https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/crizotinib]. Accessed on: November 8, 2018.</ref> It is an [[ALK inhibitor]]. | ||
*Lung cancer with ROS1 rearrangement.<ref name=pmid25264305>{{Cite journal | last1 = Shaw | first1 = AT. | last2 = Ou | first2 = SH. | last3 = Bang | first3 = YJ. | last4 = Camidge | first4 = DR. | last5 = Solomon | first5 = BJ. | last6 = Salgia | first6 = R. | last7 = Riely | first7 = GJ. | last8 = Varella-Garcia | first8 = M. | last9 = Shapiro | first9 = GI. | title = Crizotinib in ROS1-rearranged non-small-cell lung cancer. | journal = N Engl J Med | volume = 371 | issue = 21 | pages = 1963-71 | month = Nov | year = 2014 | doi = 10.1056/NEJMoa1406766 | PMID = 25264305 }}</ref> | *Lung cancer with ROS1 rearrangement.<ref name=pmid25264305>{{Cite journal | last1 = Shaw | first1 = AT. | last2 = Ou | first2 = SH. | last3 = Bang | first3 = YJ. | last4 = Camidge | first4 = DR. | last5 = Solomon | first5 = BJ. | last6 = Salgia | first6 = R. | last7 = Riely | first7 = GJ. | last8 = Varella-Garcia | first8 = M. | last9 = Shapiro | first9 = GI. | title = Crizotinib in ROS1-rearranged non-small-cell lung cancer. | journal = N Engl J Med | volume = 371 | issue = 21 | pages = 1963-71 | month = Nov | year = 2014 | doi = 10.1056/NEJMoa1406766 | PMID = 25264305 }}</ref> | ||
Revision as of 23:58, 17 March 2019
Crizotinib a drug used to treat lung cancer. Its' trade name is Xalkori (Pfizer).[1] It is an ALK inhibitor.
- Lung cancer with ROS1 rearrangement.[2]
- Lung carcinoma with ALK rearrangement.[3]
- Lung carcinoma with MET amplification.[4]
See also
References
- ↑ URL: https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/crizotinib. Accessed on: November 8, 2018.
- ↑ Shaw, AT.; Ou, SH.; Bang, YJ.; Camidge, DR.; Solomon, BJ.; Salgia, R.; Riely, GJ.; Varella-Garcia, M. et al. (Nov 2014). "Crizotinib in ROS1-rearranged non-small-cell lung cancer.". N Engl J Med 371 (21): 1963-71. doi:10.1056/NEJMoa1406766. PMID 25264305.
- ↑ Wu, YL.; Lu, S.; Lu, Y.; Zhou, J.; Shi, YK.; Sriuranpong, V.; Ho, JCM.; Ong, CK. et al. (Jun 2018). "Results of PROFILE 1029, a Phase III Comparison of First-Line Crizotinib versus Chemotherapy in East Asian Patients with ALK-Positive Advanced Non-Small Cell Lung Cancer.". J Thorac Oncol. doi:10.1016/j.jtho.2018.06.012. PMID 29966800.
- ↑ Forde, PM.; Rudin, CM. (Jun 2012). "Crizotinib in the treatment of non-small-cell lung cancer.". Expert Opin Pharmacother 13 (8): 1195-201. doi:10.1517/14656566.2012.688029. PMID 22594847.