Common variable immunodeficiency

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Common variable immunodeficiency, abbreviated CVID, is a group of genetic disorders characterized by deficient antibody production.

General

Features:^[1]

Recurrent sinus and pulmonary infections.
Inflammatory bowel disease-like disease.

Microscopic

Features:

Plasma cells absent.^[1]

Notes:

This is a favourite topic of R. Riddell.

References

↑ ^1.0 ^1.1 Agarwal S, Smereka P, Harpaz N, Cunningham-Rundles C, Mayer L (July 2010). "Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease". Inflamm Bowel Dis. doi:10.1002/ibd.21376. PMID 20629103.

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Haematopathology