Difference between revisions of "Colorectal xanthomatous polyp"

From Libre Pathology
Jump to navigation Jump to search
(+synonyms)
Line 1: Line 1:
The '''colorectal xanthomatous polyp''', also '''colorectal xanthoma''', is a rare benign [[intestinal polyp]].
The '''colorectal xanthomatous polyp''', also '''colorectal xanthoma''', is a rare benign [[intestinal polyp]].
'''Rectal xanthoma''', '''colonic xanthoma''', '''rectal xanthelasma''' and '''colonic xanthelasma''' redirect here.


==General==
==General==

Revision as of 13:26, 20 March 2014

The colorectal xanthomatous polyp, also colorectal xanthoma, is a rare benign intestinal polyp.

Rectal xanthoma, colonic xanthoma, rectal xanthelasma and colonic xanthelasma redirect here.

General

  • Rare.[1]
  • May be associated with hyperlipidemia (7/25 patients in one series[2]).

Gross

  • Yellow or cream colour.[1]

Microscopic

Features:

  • Abundant foamy histiocytes in the superficial lamina propria.
  • +/-Superficial serrations (hyperplastic features).
    • Seen in ~80% of cases.[2]

DDx:

IHC

  • CD68 +ve (foamy histiocytes).[1]

Sign out

POLYP, SIGMOID COLON, POLYPECTOMY:
- XANTHOMATOUS POLYP WITH HYPERPLASTIC FEATURES.
- NEGATIVE FOR DYSPLASIA.

COMMENT:
Xanthomatous polyps may be seen in the context of hyperlipidemia.

See also

References

  1. 1.0 1.1 1.2 Miliauskas, JR. (Apr 2002). "Rectosigmoid (colonic) xanthoma: a report of four cases and review of the literature.". Pathology 34 (2): 144-7. PMID 12009096.
  2. 2.0 2.1 Nakasono, M.; Hirokawa, M.; Muguruma, N.; Okahisa, T.; Okamura, S.; Ito, S.; Miyamoto, H.; Wada, S. et al. (Jan 2004). "Colorectal xanthomas with polypoid lesion: report of 25 cases.". APMIS 112 (1): 3-10. PMID 14961968.