Difference between revisions of "Collagenous sprue"

From Libre Pathology
Jump to navigation Jump to search
(→‎See also: +CC link)
(→‎General: more)
Line 3: Line 3:
==General==
==General==
*Thought to be related to [[celiac sprue]] - though somewhat controversial.<ref name=pmid21631278>{{Cite journal  | last1 = Zhao | first1 = X. | last2 = Johnson | first2 = RL. | title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. | journal = Arch Pathol Lab Med | volume = 135 | issue = 6 | pages = 803-9 | month = Jun | year = 2011 | doi = 10.1043/2010-0028-RS.1 | PMID = 21631278 }}</ref><ref name=pmid23735026>{{Cite journal  | last1 = Busto-Bea | first1 = V. | last2 = Crespo-Pérez | first2 = L. | last3 = García-Miralles | first3 = N. | last4 = Ruiz-Del-Árbol-Olmos | first4 = L. | last5 = Cano-Ruiz | first5 = A. | title = Collagenous sprue: Don´t forget connective tissue in chronic diarrhea evaluation. | journal = Rev Esp Enferm Dig | volume = 105 | issue = 3 | pages = 171-174 | month = May | year = 2013 | doi =  | PMID = 23735026 }}</ref>
*Thought to be related to [[celiac sprue]] - though somewhat controversial.<ref name=pmid21631278>{{Cite journal  | last1 = Zhao | first1 = X. | last2 = Johnson | first2 = RL. | title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. | journal = Arch Pathol Lab Med | volume = 135 | issue = 6 | pages = 803-9 | month = Jun | year = 2011 | doi = 10.1043/2010-0028-RS.1 | PMID = 21631278 }}</ref><ref name=pmid23735026>{{Cite journal  | last1 = Busto-Bea | first1 = V. | last2 = Crespo-Pérez | first2 = L. | last3 = García-Miralles | first3 = N. | last4 = Ruiz-Del-Árbol-Olmos | first4 = L. | last5 = Cano-Ruiz | first5 = A. | title = Collagenous sprue: Don´t forget connective tissue in chronic diarrhea evaluation. | journal = Rev Esp Enferm Dig | volume = 105 | issue = 3 | pages = 171-174 | month = May | year = 2013 | doi =  | PMID = 23735026 }}</ref>
Clinical:
*Diarrhea.
**Not responsive to Gluten-free diet.


==Microscopic==
==Microscopic==

Revision as of 03:31, 9 June 2013

Collagenous sprue is a very rare disorder of the small bowel is approximately 60 reported cases.[1]

General

Clinical:

  • Diarrhea.
    • Not responsive to Gluten-free diet.

Microscopic

Features:[1]

  • Subepithelial collagen layer > 12 micrometres - key feature.
  • Villous atrophy.
  • Crypt atrophy.

DDx:

See also

References

  1. 1.0 1.1 1.2 Zhao, X.; Johnson, RL. (Jun 2011). "Collagenous sprue: a rare, severe small-bowel malabsorptive disorder.". Arch Pathol Lab Med 135 (6): 803-9. doi:10.1043/2010-0028-RS.1. PMID 21631278.
  2. Busto-Bea, V.; Crespo-Pérez, L.; García-Miralles, N.; Ruiz-Del-Árbol-Olmos, L.; Cano-Ruiz, A. (May 2013). "Collagenous sprue: Don´t forget connective tissue in chronic diarrhea evaluation.". Rev Esp Enferm Dig 105 (3): 171-174. PMID 23735026.