Difference between revisions of "Chondromyxoid fibroma"

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DDx:
DDx:
*[[Phosphaturic mesenchymal tumour]] - case report.<ref>{{Cite journal  | last1 = Suryawanshi | first1 = P. | last2 = Agarwal | first2 = M. | last3 = Dhake | first3 = R. | last4 = Desai | first4 = S. | last5 = Rekhi | first5 = B. | last6 = Reddy | first6 = KB. | last7 = Jambhekar | first7 = NA. | title = Phosphaturic mesenchymal tumor with chondromyxoid fibroma-like feature: an unusual morphological appearance. | journal = Skeletal Radiol | volume = 40 | issue = 11 | pages = 1481-5 | month = Nov | year = 2011 | doi = 10.1007/s00256-011-1159-6 | PMID = 21533894 }}</ref>
*[[Phosphaturic mesenchymal tumour]] - case report.<ref>{{Cite journal  | last1 = Suryawanshi | first1 = P. | last2 = Agarwal | first2 = M. | last3 = Dhake | first3 = R. | last4 = Desai | first4 = S. | last5 = Rekhi | first5 = B. | last6 = Reddy | first6 = KB. | last7 = Jambhekar | first7 = NA. | title = Phosphaturic mesenchymal tumor with chondromyxoid fibroma-like feature: an unusual morphological appearance. | journal = Skeletal Radiol | volume = 40 | issue = 11 | pages = 1481-5 | month = Nov | year = 2011 | doi = 10.1007/s00256-011-1159-6 | PMID = 21533894 }}</ref>
 
*Chondroblastoma
**Also produces immature cartilage but
**Epiphyseal location
**Chicken-wire calcifications
*Chondrosarcoma
**Mature hyaline cartilage formation
**Tumor permeation of the surrounding bone
**Mitotic activity
Images:
Images:
*[http://www.webpathology.com/image.asp?n=7&Case=331 Chondromyxoid fibroma - low mag. (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=7&Case=331 Chondromyxoid fibroma - low mag. (webpathology.com)].

Revision as of 11:11, 12 November 2014

Chondromyxoid fibroma is a rare benign chondro-osseous tumour typically found in the metaphysis of teenagers or young adults.

General

  • Uncommon and benign.[1]
  • Teenagers or young adults.

Gross

  • Metaphyseal lesion - classic location.[2]
  • Well-circumscribed.
  • Fragments of white-grey rubbery tissue

Microscopic

Features:[3]

  • Spindle cells or stellate cells in a myxoid or chondroid stroma.

DDx:

  • Phosphaturic mesenchymal tumour - case report.[4]
  • Chondroblastoma
    • Also produces immature cartilage but
    • Epiphyseal location
    • Chicken-wire calcifications
  • Chondrosarcoma
    • Mature hyaline cartilage formation
    • Tumor permeation of the surrounding bone
    • Mitotic activity

Images:

See also

References

  1. Bhamra, JS.; Al-Khateeb, H.; Dhinsa, BS.; Gikas, PD.; Tirabosco, R.; Pollock, RC.; Skinner, JA.; Aston, WJ. et al. (2014). "Chondromyxoid fibroma management: a single institution experience of 22 cases.". World J Surg Oncol 12: 283. doi:10.1186/1477-7819-12-283. PMID 25217119.
  2. Budny, AM.; Ismail, A.; Osher, L.. "Chondromyxoid fibroma.". J Foot Ankle Surg 47 (2): 153-9. doi:10.1053/j.jfas.2007.08.013. PMID 18312923.
  3. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 642. ISBN 978-0781765275.
  4. Suryawanshi, P.; Agarwal, M.; Dhake, R.; Desai, S.; Rekhi, B.; Reddy, KB.; Jambhekar, NA. (Nov 2011). "Phosphaturic mesenchymal tumor with chondromyxoid fibroma-like feature: an unusual morphological appearance.". Skeletal Radiol 40 (11): 1481-5. doi:10.1007/s00256-011-1159-6. PMID 21533894.