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Clinical history
41 year old man, watery diarrhea and abdominal pain.
Site
Colon biopsy.
Primary image
Intermediate magnification. H&E stain.
High magnification
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High magnification. H&E stain.
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Very high magnification
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Very high magnification. H&E stain.
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Differential diagnosis
Additional tests
More history
More history
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No family history of IBD. Diarrhea several weeks. Well prior to diarrhea. Medications: one anti-hypertensive.
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Ask a friend
Ask a friend
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Did you see anything at high magnification?
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Stains
Alcian blue/PAS to Bilirubin |
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Test | Result |
Alcian blue/PAS | Dr Torres would ask why! |
Alican blue pH 1.0 | Dr Torres would ask why! |
Alcian blue pH 2.5 | Dr Torres would ask why! |
Auramine | Dr Torres would ask why! |
Bielchowsky | Dr Torres would ask why! |
Bilirubin | Dr Torres would ask why! |
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Colloidal iron to Fontana-Masson |
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Test | Result |
Colloidal iron | Dr Torres would ask why! |
Congo red | Dr Torres would ask why! |
Cresyl violet | Dr Torres would ask why! |
Dieterle | Dr Torres would ask why! |
Diff Quik | Dr Torres would ask why! |
Fontana-Masson | Dr Torres would ask why! |
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Gallyas to Gremelius |
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Test | Result |
Gallyas | Dr Torres would ask why! |
Giemsa | Dr Torres would ask why! |
GMS | Dr Torres would ask why! |
Gomori's trichrome | Dr Torres would ask why! |
Gram | Dr Torres would ask why! |
Gremelius | Dr Torres would ask why! |
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JMS to Mucicarmine |
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Test | Result |
JMS | Dr Torres would ask why! |
Jones | Dr Torres would ask why! |
Kinyoun | Dr Torres would ask why! |
Luxol fast blue | Dr Torres would ask why! |
Masson trichrome | Dr Torres would ask why! |
M-MAS | Dr Torres would ask why! |
Movat | Dr Torres would ask why! |
Mucicarmine | Dr Torres would ask why! |
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Oil red O to Prussian blue |
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Test | Result |
Oil red O | Dr Torres would ask why! |
Orecein | Dr Torres would ask why! |
PAS | Dr Torres would ask why! |
PASD | Dr Torres would ask why! |
PASF | Dr Torres would ask why! |
PTAH | Dr Torres would ask why! |
Prussian blue | Dr Torres would ask why! |
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Reticulin to Ziehl-Neelsen |
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Test | Result |
Reticulin | Dr Torres would ask why! |
Sudan black B | Dr Torres would ask why! |
Toluidine blue | Dr Torres would ask why! |
Verhoeff | Dr Torres would ask why! |
Von Kossa | Dr Torres would ask why! |
Warthin-Starry | Spirochetes |
Ziehl-Neeslen | Dr Torres would ask why! |
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IHC
Alpha-1 AT to Cathepsin K |
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Test | Result |
alpha-1 AT | Dr T would ask why! |
ACTH | Dr T would ask why! |
AE1/AE1 | Dr T would ask why! |
alpha-fetoprotein | Dr T would ask why! |
Alk-I | Dr T would ask why! |
AMACR | Dr T would ask why! |
AR | Dr T would ask why! |
ATRX | Dr T would ask why! |
Beta2-microglobulin | Dr T would ask why! |
B72.3 | Dr T would ask why! |
Beta-catenin | Dr T would ask why! |
BCL2 | Dr T would ask why! |
BCL6 | Dr T would ask why! |
BCLxL | Dr T would ask why! |
C3 comp | Dr T would ask why! |
CA9 | Dr T would ask why! |
Calcitonin | Dr T would ask why! |
Calponin | Dr T would ask why! |
Calretinin | Dr T would ask why! |
CAM5.2 | Dr T would ask why! |
Cathepsin K | Dr T would ask why! |
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CD10 to Chromogranin |
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Test | Result |
CD10 | Dr T would ask why! |
CD117 | Dr T would ask why! |
CD138 | Dr T would ask why! |
CD15 | Dr T would ask why! |
CD1a | Dr T would ask why! |
CD20 | Dr T would ask why! |
CD21 | Dr T would ask why! |
CD23 | Dr T would ask why! |
CD3 | Dr T would ask why! |
CD30 | Dr T would ask why! |
CD31 | Dr T would ask why! |
CD34 | Dr T would ask why! |
CD35 | Dr T would ask why! |
CD4 | Dr T would ask why! |
CD43 | Dr T would ask why! |
CD45 (LCA) | Dr T would ask why! |
CD5 | Dr T would ask why! |
CD56 | Dr T would ask why! |
CD57 | Dr T would ask why! |
CD68 | Dr T would ask why! |
CD7 | Dr T would ask why! |
CD79a | Dr T would ask why! |
CD8 | Dr T would ask why! |
CD99 | Dr T would ask why! |
CDX2 | Dr T would ask why! |
CEA-m | Dr T would ask why! |
Chromogranin | Dr T would ask why! |
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CK17 to Glypican 3 |
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Test | Result |
CK17 | Dr T would ask why! |
CK19 | Dr T would ask why! |
CK20 | Dr T would ask why! |
CK34betaE12 | Dr T would ask why! |
CK5/6 | Dr T would ask why! |
CK7 | Dr T would ask why! |
CMV | Dr T would ask why! |
c-MYC | Dr T would ask why! |
Cyclin D1 | Dr T would ask why! |
D2-40 | Dr T would ask why! |
Desmin | Dr T would ask why! |
DOG1 | Dr T would ask why! |
EBV | Dr T would ask why! |
EMA | Dr T would ask why! |
ER and PR | Dr T would ask why! |
Factor VIII | Dr T would ask why! |
Factor XIIIa | Dr T would ask why! |
Fascin | Dr T would ask why! |
FH | Dr T would ask why! |
FSH | Dr T would ask why! |
Gastrin | Dr T would ask why! |
GATA3 | Dr T would ask why! |
GCDFP-15 (BRST2) | Dr T would ask why! |
GFAP | Dr T would ask why! |
GH | Dr T would ask why! |
Glucagon | Dr T would ask why! |
Glypican-3 | Dr T would ask why! |
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HBME-1 to IgM |
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Test | Result |
HBME-1 | Dr T would ask why! |
HBV core | Dr T would ask why! |
HBV surface | Dr T would ask why! |
H-caldesmon | Dr T would ask why! |
HCG | Dr T would ask why! |
Helicobacter | Dr T would ask why! |
Hepatocyte | Dr T would ask why! |
HER2/neu | Dr T would ask why! |
HHV-8 | Dr T would ask why! |
HMB-45 | Dr T would ask why! |
HNF1beta | Dr T would ask why! |
HPV | Dr T would ask why! |
HSV-I | Dr T would ask why! |
HSV-II | Dr T would ask why! |
IDH-1 | Dr T would ask why! |
Inhibin | Dr T would ask why! |
INI1 (BAF47) | Dr T would ask why! |
Insulin | Dr T would ask why! |
Kappa | Dr T would ask why! |
Ki-67 | Dr T would ask why! |
Lambda | Dr T would ask why! |
Leu 7 | Dr T would ask why! |
IgA | Dr T would ask why! |
IgG | Dr T would ask why! |
IgM | Dr T would ask why! |
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LH to PDGFR |
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Test | Result |
LH | Dr T would ask why! |
LIN28 | Dr T would ask why! |
Lysozyme | Dr T would ask why! |
mammoglobin | Dr T would ask why! |
MAP2 | Dr T would ask why! |
MCV | Dr T would ask why! |
Melanin A | Dr T would ask why! |
MHC class I | Dr T would ask why! |
MITF | Dr T would ask why! |
MUM1 | Dr T would ask why! |
Myeloperoxidase | Dr T would ask why! |
MYO D1 | Dr T would ask why! |
Myoglobin | Dr T would ask why! |
Napsin | Dr T would ask why! |
NF | Dr T would ask why! |
NKX3.1 | Dr T would ask why! |
NSE | Dr T would ask why! |
OCT3/4 | Dr T would ask why! |
p16 | Dr T would ask why! |
P501S | Dr T would ask why! |
p53 | Dr T would ask why! |
p57 | Dr T would ask why! |
p63 | Dr T would ask why! |
Pankeratin | Dr T would ask why! |
PAX2 | Dr T would ask why! |
PAX5 | Dr T would ask why! |
PAX8 | Dr T would ask why! |
PCNA | Dr T would ask why! |
PDGFR | Dr T would ask why! |
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PLAP to WT1 |
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Test | Result |
PLAP | Dr T would ask why! |
PNL-2C | Dr T would ask why! |
Prolactin | Dr T would ask why! |
PSA | Dr T would ask why! |
PSAP | Dr T would ask why! |
RCC | Dr T would ask why! |
S-100 | Dr T would ask why! |
SALL4 | Dr T would ask why! |
Smooth muscle actin | Dr T would ask why! |
Somatostatin | Dr T would ask why! |
STAT6 | Dr T would ask why! |
Synaptophysin | Dr T would ask why! |
TdT | Dr T would ask why! |
TFE3 | Dr T would ask why! |
TFEB | Dr T would ask why! |
Thyroglobulin | Dr T would ask why! |
Toxoplasma | Dr T would ask why! |
TSH | Dr T would ask why! |
TTF-1 | Dr T would ask why! |
Ubiquitin | Dr T would ask why! |
UCHL1 (PGP9.5) | Dr T would ask why! |
Ulex Europaeus | Dr T would ask why! |
Vimentin | Dr T would ask why! |
VIP | Dr T would ask why! |
VZV | Dr T would ask why! |
WT-1 | Dr T would ask why! |
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Diagnosis
Other cases
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| Number | |
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| Subspecialty (Difficulty) |
Autopsy pathology (jr,sr, f/e)
Breast pathology (jr,sr, f/e)
Cardiovascular pathology (jr,sr, f/e)
Cytopathology (jr,sr, f/e)
Dermatopathology (jr,sr, f/e)
Endocrine pathology (jr,sr, f/e)
Forensic pathology (jr,sr, f/e)
Gastrointestinal pathology (jr,sr, f/e)
Genitourinary pathology (jr,sr, f/e)
Gynecologic pathology (jr,sr, f/e)
Hematopathology (jr,sr, f/e)
Head and neck pathology (jr,sr, f/e)
Lymph node pathology (jr,sr, f/e)
Medical kidney pathology (jr,sr, f/e)
Molecular pathology (jr,sr, f/e)
Neuropathology (jr,sr, f/e)
Pediatric pathology (jr,sr, f/e)
Pulmonary pathology (jr,sr, f/e)
Placental pathology (jr,sr, f/e)
Soft tissue pathology (jr,sr, f/e) |
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| Difficulty | |
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