Difference between revisions of "Bulbourethral gland"
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'''Bulbourethral gland''', also '''Cowper's gland''', is an accessory gland of the male reproductive system found at the apex of the [[prostate gland]]. It may be confused with [[prostate carcinoma]], especially [[foamy gland carcinoma]]. | |||
==General== | |||
*Mucinous glands at the apex of the [[prostate gland]]. | |||
==Microscopic== | |||
Features:<ref name=pmid9158679>{{Cite journal | last1 = Cina | first1 = SJ. | last2 = Silberman | first2 = MA. | last3 = Kahane | first3 = H. | last4 = Epstein | first4 = JI. | title = Diagnosis of Cowper's glands on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 21 | issue = 5 | pages = 550-5 | month = May | year = 1997 | doi = | PMID = 9158679 }}</ref> | |||
*Lobular glands with abundant pale cytoplasm. | |||
**Resemble (mucinous) [[salivary gland]]s. | |||
*Often assocatiated with skeletal muscle.<ref>URL: [http://webpathology.com/image.asp?case=21&n=4 http://webpathology.com/image.asp?case=21&n=4]. Accessed on: 3 June 2013.</ref> | |||
DDx: | |||
*[[Foamy gland carcinoma]]. | |||
*Mucinous metaplasia of the prostate. | |||
Images: | |||
*[http://pathology.mc.duke.edu/research/histo_course/mixed_saliv.jpg Mucinous/serous salivary gland (duke.edu)]. | |||
*[http://webpathology.com/image.asp?case=21&n=4 Cowper gland (webpathology.com)]. | |||
==Stains== | |||
*[[Mucicarmine]] +ve. | |||
*[[PAS-D]] +ve. | |||
==IHC== | |||
Features:<ref name=pmid9158679/> | |||
*PSAP -ve. | |||
*PSA +ve. | |||
*HMWCK +ve. | |||
==See also== | |||
*[[Prostate gland]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Prostate gland]] | |||
Revision as of 00:54, 18 April 2014
Bulbourethral gland, also Cowper's gland, is an accessory gland of the male reproductive system found at the apex of the prostate gland. It may be confused with prostate carcinoma, especially foamy gland carcinoma.
General
- Mucinous glands at the apex of the prostate gland.
Microscopic
Features:[1]
- Lobular glands with abundant pale cytoplasm.
- Resemble (mucinous) salivary glands.
- Often assocatiated with skeletal muscle.[2]
DDx:
- Foamy gland carcinoma.
- Mucinous metaplasia of the prostate.
Images:
Stains
- Mucicarmine +ve.
- PAS-D +ve.
IHC
Features:[1]
- PSAP -ve.
- PSA +ve.
- HMWCK +ve.