Difference between revisions of "BCL6"
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'''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]]. ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref> | '''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]]. ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref> | ||
==Normal staining== | |||
*Marks germinal centre cells. | |||
Note: | |||
*Usually paired with [[BCL2]] which is normally negative in germinal centres. | |||
==Pathologic positive== | |||
*[[Diffuse large B-cell lymphoma]]. | |||
Revision as of 15:55, 26 April 2022
BCL6 is a commonly used immunostain in hematopathology. BCL6 is gene and formally known as BCL6 transcription repressor.[1][2]
Normal staining
- Marks germinal centre cells.
Note:
- Usually paired with BCL2 which is normally negative in germinal centres.
Pathologic positive
See also
- BCL2.
- ↑ URL: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001. Accessed on: April 26, 2022.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 109565