Angiomyofibroblastoma

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Angiomyofibroblastoma is rare uncommon soft tissue lesion of the vulva.

General

  • Uncommon.

Clinical DDx:

Microscopic

Features:[1]

  • Hypercellular zones and hypocellular edematous zones.
  • Small blood vessels (~20 micrometers) - no large blood vessels - key feature.
  • Myxoid stroma - key feature.
  • Small stellate cell/spindle cells without significant nuclear atypia.

DDx:

Images

www:

See also

References

  1. Fletcher, CD.; Tsang, WY.; Fisher, C.; Lee, KC.; Chan, JK. (Apr 1992). "Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma.". Am J Surg Pathol 16 (4): 373-82. PMID 1314521.