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Difference between revisions of "Ampulla of Vater"
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→IHC: more
(→Ampullary carcinoma: more on prognosis) |
(→IHC: more) |
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| Line 119: | Line 119: | ||
*SMAD4 +ve/-ve. | *SMAD4 +ve/-ve. | ||
**Lost in pancreatic neoplasia ~90% of cases vs. ~35% of ampullary tumours.<ref name=pmid12640108>{{Cite journal | last1 = McCarthy | first1 = DM. | last2 = Hruban | first2 = RH. | last3 = Argani | first3 = P. | last4 = Howe | first4 = JR. | last5 = Conlon | first5 = KC. | last6 = Brennan | first6 = MF. | last7 = Zahurak | first7 = M. | last8 = Wilentz | first8 = RE. | last9 = Cameron | first9 = JL. | title = Role of the DPC4 tumor suppressor gene in adenocarcinoma of the ampulla of Vater: analysis of 140 cases. | journal = Mod Pathol | volume = 16 | issue = 3 | pages = 272-8 | month = Mar | year = 2003 | doi = 10.1097/01.MP.0000057246.03448.26 | PMID = 12640108 }}</ref> | **Lost in pancreatic neoplasia ~90% of cases vs. ~35% of ampullary tumours.<ref name=pmid12640108>{{Cite journal | last1 = McCarthy | first1 = DM. | last2 = Hruban | first2 = RH. | last3 = Argani | first3 = P. | last4 = Howe | first4 = JR. | last5 = Conlon | first5 = KC. | last6 = Brennan | first6 = MF. | last7 = Zahurak | first7 = M. | last8 = Wilentz | first8 = RE. | last9 = Cameron | first9 = JL. | title = Role of the DPC4 tumor suppressor gene in adenocarcinoma of the ampulla of Vater: analysis of 140 cases. | journal = Mod Pathol | volume = 16 | issue = 3 | pages = 272-8 | month = Mar | year = 2003 | doi = 10.1097/01.MP.0000057246.03448.26 | PMID = 12640108 }}</ref> | ||
*p53 +ve ~55 of cases.<ref name=pmid11144926>{{Cite journal | last1 = Takashima | first1 = M. | last2 = Ueki | first2 = T. | last3 = Nagai | first3 = E. | last4 = Yao | first4 = T. | last5 = Yamaguchi | first5 = K. | last6 = Tanaka | first6 = M. | last7 = Tsuneyoshi | first7 = M. | title = Carcinoma of the ampulla of Vater associated with or without adenoma: a clinicopathologic analysis of 198 cases with reference to p53 and Ki-67 immunohistochemical expressions. | journal = Mod Pathol | volume = 13 | issue = 12 | pages = 1300-7 | month = Dec | year = 2000 | doi = 10.1038/modpathol.3880238 | PMID = 11144926 }}</ref> | |||
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