Difference between revisions of "Alpha-fetoprotein"

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{{ Infobox immunostain
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Abbrev    = AFP
| Synonyms  =
| Similar    =
| Clones    =     
| Use        =
| Subspecial = [[genitourinary pathology]], [[gastrointestinal pathology]] 
| Pattern    =
| Positive  = [[yolk sac tumour]], [[hepatocellular carcinoma]]
| Negative  =
| Other      = common serum tumour marker
}}
'''Alpha-fetoprotein''', abbreviated '''AFP''', is plasma protein seen in fetal life and produced by various tumours.
'''Alpha-fetoprotein''', abbreviated '''AFP''', is plasma protein seen in fetal life and produced by various tumours.


==Elevated AFP - classic causes==
==Elevated AFP - classic causes==
*[[Yolk sac tumour]].
*[[Yolk sac tumour]].
*[[Hepatocellular carcinoma]].
*[[Hepatocellular carcinoma]].<ref name=pmid26157947>{{Cite journal  | last1 = Ip | first1 = S. | last2 = Schaeffer | first2 = DF. | last3 = Yoshida | first3 = EM. | last4 = Kwan | first4 = WP. | title = Alpha Fetoprotein-Secreting Gastric Cancer in the Setting of Chronic Hepatitis B: The Role of Endoscopy. | journal = ACG Case Rep J | volume = 2 | issue = 3 | pages = 152-4 | month = Apr | year = 2015 | doi = 10.14309/crj.2015.38 | PMID = 26157947 }}</ref>


==Uncommon==
==Uncommon==

Revision as of 00:42, 30 September 2015

Alpha-fetoprotein
Immunostain in short
Abbreviation AFP
Subspeciality genitourinary pathology, gastrointestinal pathology
Positive yolk sac tumour, hepatocellular carcinoma
Other common serum tumour marker

Alpha-fetoprotein, abbreviated AFP, is plasma protein seen in fetal life and produced by various tumours.

Elevated AFP - classic causes

Uncommon

See also

References

  1. 1.0 1.1 Ip, S.; Schaeffer, DF.; Yoshida, EM.; Kwan, WP. (Apr 2015). "Alpha Fetoprotein-Secreting Gastric Cancer in the Setting of Chronic Hepatitis B: The Role of Endoscopy.". ACG Case Rep J 2 (3): 152-4. doi:10.14309/crj.2015.38. PMID 26157947.
  2. Anzai, H.; Kazama, S.; Kiyomatsu, T.; Nishikawa, T.; Tanaka, T.; Tanaka, J.; Hata, K.; Kawai, K. et al. (2015). "Alpha-fetoprotein-producing early rectal carcinoma: a rare case report and review.". World J Surg Oncol 13: 180. doi:10.1186/s12957-015-0590-x. PMID 25962419.