Difference between revisions of "Alpha-fetoprotein"
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{{ Infobox immunostain | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
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| Caption = | |||
| Abbrev = AFP | |||
| Synonyms = | |||
| Similar = | |||
| Clones = | |||
| Use = | |||
| Subspecial = [[genitourinary pathology]], [[gastrointestinal pathology]] | |||
| Pattern = | |||
| Positive = [[yolk sac tumour]], [[hepatocellular carcinoma]] | |||
| Negative = | |||
| Other = common serum tumour marker | |||
}} | |||
'''Alpha-fetoprotein''', abbreviated '''AFP''', is plasma protein seen in fetal life and produced by various tumours. | '''Alpha-fetoprotein''', abbreviated '''AFP''', is plasma protein seen in fetal life and produced by various tumours. | ||
==Elevated AFP - classic causes== | ==Elevated AFP - classic causes== | ||
*[[Yolk sac tumour]]. | *[[Yolk sac tumour]]. | ||
*[[Hepatocellular carcinoma]]. | *[[Hepatocellular carcinoma]].<ref name=pmid26157947>{{Cite journal | last1 = Ip | first1 = S. | last2 = Schaeffer | first2 = DF. | last3 = Yoshida | first3 = EM. | last4 = Kwan | first4 = WP. | title = Alpha Fetoprotein-Secreting Gastric Cancer in the Setting of Chronic Hepatitis B: The Role of Endoscopy. | journal = ACG Case Rep J | volume = 2 | issue = 3 | pages = 152-4 | month = Apr | year = 2015 | doi = 10.14309/crj.2015.38 | PMID = 26157947 }}</ref> | ||
==Uncommon== | ==Uncommon== |
Revision as of 00:42, 30 September 2015
Alpha-fetoprotein | |
---|---|
Immunostain in short | |
Abbreviation | AFP |
Subspeciality | genitourinary pathology, gastrointestinal pathology |
Positive | yolk sac tumour, hepatocellular carcinoma |
Other | common serum tumour marker |
Alpha-fetoprotein, abbreviated AFP, is plasma protein seen in fetal life and produced by various tumours.
Elevated AFP - classic causes
Uncommon
See also
References
- ↑ 1.0 1.1 Ip, S.; Schaeffer, DF.; Yoshida, EM.; Kwan, WP. (Apr 2015). "Alpha Fetoprotein-Secreting Gastric Cancer in the Setting of Chronic Hepatitis B: The Role of Endoscopy.". ACG Case Rep J 2 (3): 152-4. doi:10.14309/crj.2015.38. PMID 26157947.
- ↑ Anzai, H.; Kazama, S.; Kiyomatsu, T.; Nishikawa, T.; Tanaka, T.; Tanaka, J.; Hata, K.; Kawai, K. et al. (2015). "Alpha-fetoprotein-producing early rectal carcinoma: a rare case report and review.". World J Surg Oncol 13: 180. doi:10.1186/s12957-015-0590-x. PMID 25962419.