Difference between revisions of "Adamantinoma"

From Libre Pathology
Jump to navigation Jump to search
(+cat.)
(split out)
Line 1: Line 1:
#redirect [[Chondro-osseous tumours#Adamantinoma]]
'''Adamantinoma''' is an uncommon benign [[bone tumour]]. It should '''not''' be confused with ''[[adenomatoid tumour]]''.
 
==General==
Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref>
*Rare: < 1% of bone tumours.
*25-35 years old.
*Benign, may be locally aggressive.
*Cousin of [[ameloblastoma]]. (???)
 
==Gross==
*Tibia or fibula.
 
===Radiology===
*Intracortical, radiolucent.
 
==Microscopic==
Features:
*Biphasic tumour:
*#Fibrous/spindle cell component.
*#Epithelial component.
 
DDx:<ref name=pathcon_adam>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2]. Accessed on: 28 April 2011.</ref>
*Vascular tumours ([[Epithelioid hemangioendothelioma]]).
*[[Metastatic carcinoma]].
 
===Images===
<gallery>
Image:Adamantinoma_-_intermed_mag.jpg | Adamantinoma - intermed. mag. (WC)
</gallery>
www:
*[http://southbaypath.org/CaseImages/sb5260/AdamantinomaBiopsy3.jpg Adamantinoma (southbaypath.org)].<ref>URL: [http://southbaypath.org/CaseImages/sb5260/sb5260.htm http://southbaypath.org/CaseImages/sb5260/sb5260.htm]. Accessed on: 7 December 2010.</ref>
 
==IHC==
Features:<ref name=pathcon_adam/>
*CK14 +ve (HMWK).<ref>URL: [http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]. Accessed on: 28 April 2011.</ref>
*CK19 +ve (LMWK).
*CK8/18 -ve (LMWK).
 
==See also==
*[[Chondro-osseous tumours]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Chondro-osseous tumours]]

Revision as of 22:01, 29 August 2013

Adamantinoma is an uncommon benign bone tumour. It should not be confused with adenomatoid tumour.

General

Features:[1]

  • Rare: < 1% of bone tumours.
  • 25-35 years old.
  • Benign, may be locally aggressive.
  • Cousin of ameloblastoma. (???)

Gross

  • Tibia or fibula.

Radiology

  • Intracortical, radiolucent.

Microscopic

Features:

  • Biphasic tumour:
    1. Fibrous/spindle cell component.
    2. Epithelial component.

DDx:[2]

Images

www:

IHC

Features:[2]

  • CK14 +ve (HMWK).[4]
  • CK19 +ve (LMWK).
  • CK8/18 -ve (LMWK).

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 650. ISBN 978-0781765275.
  2. 2.0 2.1 URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2. Accessed on: 28 April 2011.
  3. URL: http://southbaypath.org/CaseImages/sb5260/sb5260.htm. Accessed on: 7 December 2010.
  4. URL: http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm. Accessed on: 28 April 2011.