Difference between revisions of "Acquired cystic disease of the kidney"

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#redirect [[Cystic kidney diseases#Acquired renal cystic disease]]
'''Acquired cystic disease of the kidney''' (abbreviated '''ACDK'''), also '''acquired cystic disease''', is a benign change of the [[kidney]] seen in chronic renal failure.


''Acquired renal cystic disease'' and ''acquired cystic renal disease'' redirect here.
==General==
*Thought to arise due to uremia,<ref name=pmid7861721>{{cite journal |author=Fick GM, Gabow PA |title=Hereditary and acquired cystic disease of the kidney |journal=Kidney Int. |volume=46 |issue=4 |pages=951–64 |year=1994 |month=October |pmid=7861721 |doi= |url=http://www.nature.com/ki/journal/v46/n4/pdf/ki1994354a.pdf}}</ref> not specific to the type of renal dialysis, i.e. hemodialysis vs. peritoneal dialysis.
*Presence of cysts dependent on duration of dialysis:<ref name=pmid7861721/>
**< 3 years ~44%.
**>4 years ~80%.
**>10 years ~90%.
*Associated with renal cell carcinoma - specifically ''[[acquired cystic disease-associated renal cell carcinoma]]''.<ref name=pmid16434887>{{Cite journal  | last1 = Tickoo | first1 = SK. | last2 = dePeralta-Venturina | first2 = MN. | last3 = Harik | first3 = LR. | last4 = Worcester | first4 = HD. | last5 = Salama | first5 = ME. | last6 = Young | first6 = AN. | last7 = Moch | first7 = H. | last8 = Amin | first8 = MB. | title = Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. | journal = Am J Surg Pathol | volume = 30 | issue = 2 | pages = 141-53 | month = Feb | year = 2006 | doi =  | PMID = 16434887 }}</ref>
==Microscopic==
Features:<ref name=pmid1819219>{{cite journal |author=Kessler M, Testevuide P, Aymard B, Huu TC |title=Acquired renal cystic disease mimicking adult polycystic kidney disease in a patient undergoing long-term hemodialysis |journal=Am. J. Nephrol. |volume=11 |issue=6 |pages=513–7 |year=1991 |pmid=1819219 |doi= |url=}}</ref>
*Cysts - location: cortex and medulla.
**Lined by simple flattened epithelium.
DDx:
*[[Autosomal dominant polycystic kidney disease]] rarely,<ref name=pmid1819219>{{cite journal |author=Kessler M, Testevuide P, Aymard B, Huu TC |title=Acquired renal cystic disease mimicking adult polycystic kidney disease in a patient undergoing long-term hemodialysis |journal=Am. J. Nephrol. |volume=11 |issue=6 |pages=513–7 |year=1991 |pmid=1819219 |doi= |url=}}</ref> see ''Microscopic'' in [[ADPKD]].
*[[Acquired cystic disease-associated renal cell carcinoma]].
*[[Papillary renal cell carcinoma]].
==See also==
*[[Cystic kidney diseases]].
==References==
{{Reflist|1}}
[[Category:Genitourinary pathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 04:07, 27 April 2016

Acquired cystic disease of the kidney (abbreviated ACDK), also acquired cystic disease, is a benign change of the kidney seen in chronic renal failure.

Acquired renal cystic disease and acquired cystic renal disease redirect here.

General

  • Thought to arise due to uremia,[1] not specific to the type of renal dialysis, i.e. hemodialysis vs. peritoneal dialysis.
  • Presence of cysts dependent on duration of dialysis:[1]
    • < 3 years ~44%.
    • >4 years ~80%.
    • >10 years ~90%.
  • Associated with renal cell carcinoma - specifically acquired cystic disease-associated renal cell carcinoma.[2]

Microscopic

Features:[3]

  • Cysts - location: cortex and medulla.
    • Lined by simple flattened epithelium.

DDx:

See also

References

  1. ↑ 1.0 1.1 Fick GM, Gabow PA (October 1994). "Hereditary and acquired cystic disease of the kidney". Kidney Int. 46 (4): 951–64. PMID 7861721. http://www.nature.com/ki/journal/v46/n4/pdf/ki1994354a.pdf.
  2. ↑ Tickoo, SK.; dePeralta-Venturina, MN.; Harik, LR.; Worcester, HD.; Salama, ME.; Young, AN.; Moch, H.; Amin, MB. (Feb 2006). "Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia.". Am J Surg Pathol 30 (2): 141-53. PMID 16434887.
  3. ↑ 3.0 3.1 Kessler M, Testevuide P, Aymard B, Huu TC (1991). "Acquired renal cystic disease mimicking adult polycystic kidney disease in a patient undergoing long-term hemodialysis". Am. J. Nephrol. 11 (6): 513–7. PMID 1819219.
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