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Difference between revisions of "Acquired cystic disease-associated renal cell carcinoma"
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Acquired cystic disease-associated renal cell carcinoma (view source)
Revision as of 12:53, 21 April 2016
, 12:53, 21 April 2016no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
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| Synonyms = | |||
| Micro = sieve-like architecture (tubular structures/cribriforming), oxylate crystals | |||
| Subtypes = | |||
| LMDDx = [[acquired cystic renal disease]], [[papillary renal cell carcinoma]], [[hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]] | |||
| Stains = | |||
| IHC = AMACR +ve, CD10 +ve, pankeratin +ve, CK7 +ve (heterogeneous), EMA -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = kidney with cystic changes, thinned cortex | |||
| Grossing = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]] | |||
| Staging = [[kidney cancer staging]] | |||
| Site = [[kidney]] - see [[kidney tumours]] | |||
| Assdx = [[end-stage renal disease]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Acquired cystic disease-associated renal cell carcinoma''', abbreviated '''ACD-RCC''', is a rare [[kidney cancer]] that arises in the context of [[chronic renal failure]]. | '''Acquired cystic disease-associated renal cell carcinoma''', abbreviated '''ACD-RCC''', is a rare [[kidney cancer]] that arises in the context of [[chronic renal failure]]. | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Tubular | *Tubular structures with cribriforming/a sieve-like architecture.<ref>{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | last3 = Eble | first3 = JN. | last4 = Egevad | first4 = L. | last5 = Epstein | first5 = JI. | last6 = Grignon | first6 = D. | last7 = Hes | first7 = O. | last8 = Moch | first8 = H. | last9 = Montironi | first9 = R. | title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. | journal = Am J Surg Pathol | volume = 37 | issue = 10 | pages = 1469-89 | month = Oct | year = 2013 | doi = 10.1097/PAS.0b013e318299f2d1 | PMID = 24025519 }} | ||
</ref> | </ref> | ||
**[[Hobnail]] cells. | **[[Hobnail]] cells. | ||