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This article covers ''[[serous fat atrophy]]'' as it is classically seen in starvation. | This article covers ''[[serous fat atrophy]]'' as it is classically seen in starvation. | ||
''Cachexia'' and ''dystrophic mesenteric adipocytes'' direct here. | |||
=Starvation= | =Starvation= | ||
===Causes of starvation=== | ===Causes of starvation=== | ||
*Psychiatric: | *Psychiatric: | ||
**Dementia. | **[[Dementia]]. | ||
**Anorexia nervosa. | **Anorexia nervosa. | ||
**Disorder with delusions, e.g. schizophrenia, bipolar affective disorder - belief one is being poisoned. | **Disorder with delusions, e.g. schizophrenia, bipolar affective disorder - belief one is being poisoned. | ||
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DDx: | DDx: | ||
*[[Signet ring cell carcinoma]].<ref name=pmid6222282>{{Cite journal | last1 = Clarke | first1 = BE. | last2 = Brown | first2 = DJ. | last3 = Xipell | first3 = JM. | title = Gelatinous transformation of the bone marrow. | journal = Pathology | volume = 15 | issue = 1 | pages = 85-8 | month = Jan | year = 1983 | doi = | PMID = 6222282 }}</ref> | *[[Signet ring cell carcinoma]].<ref name=pmid6222282>{{Cite journal | last1 = Clarke | first1 = BE. | last2 = Brown | first2 = DJ. | last3 = Xipell | first3 = JM. | title = Gelatinous transformation of the bone marrow. | journal = Pathology | volume = 15 | issue = 1 | pages = 85-8 | month = Jan | year = 1983 | doi = | PMID = 6222282 }}</ref> | ||
*[[Liposarcoma]]. | |||
*[[Malignant mesothelioma]]. | |||
*[[Vascular lesions]]. | |||
====Images==== | ====Images==== | ||
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Image:Fat_atrophy_-_very_high_mag.jpg | Serous fat atrophy - very high mag. (WC) | Image:Fat_atrophy_-_very_high_mag.jpg | Serous fat atrophy - very high mag. (WC) | ||
</gallery> | </gallery> | ||
===IHC=== | |||
Features:<ref>{{cite journal |authors=van Haeringen B, Francis L, Olive E, James D |title=Adipocyte Atrophy Mimicking Signet Ring Cell Carcinoma of the Gallbladder |journal=Case Rep Pathol |volume=2021 |issue= |pages=4676885 |date=2021 |pmid=34754523 |pmc=8572618 |doi=10.1155/2021/4676885 |url=}}</ref> | |||
*S-100 +ve (key stain). | |||
*AE1/AE3 -ve (key stain). | |||
*CD68 -ve. | |||
=See also= | =See also= |
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