Keloid

From Libre Pathology
Revision as of 22:28, 21 August 2013 by Michael (talk | contribs) (split-out)
Jump to navigation Jump to search

Keloid is an uncommon abnormal scarring.

Keloid
Diagnosis in short

Keloid. H&E stain.

LM thick collagen bundles - surrounded by paler staining fibroblasts, loss of adnexal structures
LM DDx hypertrophic scar
Site skin

Clinical history typically dark skinned individuals
Prognosis benign
Hypertrophic scar redirects here.

General

  • Sites of previous trauma/surgery, esp. in dark skinned individuals.[1]

Note:

  • Reported as "keloidal-type collagen"; the clinician decides between hypertrophic scar and keloid.

Microscopic

Features:[1]

  • Thick collagen bundles - surrounded by paler staining fibroblasts - key feature.
  • Lesion replaces adnexal structures, e.g. hair, sweat glands.

DDx:

  • Hypertrophic scar.[2]

Images

www:

Sign out

SKIN LESION, LEFT SCAPULA, EXCISION:
- DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, SEE COMMENT.

COMMENT:
The findings are consistent with a hypertrophic scar or keloid; clinical correlation is required.

Clinical provided

SKIN LESION, LEFT NIPPLE AREOLA, EXCISION:
- DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, CONSISTENT WITH HYPERTROPHIC SCAR.

See also

References

{{Reflist|1}

  1. 1.0 1.1 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 492. ISBN 978-0781765275.
  2. Gauglitz, GG.; Korting, HC.; Pavicic, T.; Ruzicka, T.; Jeschke, MG.. "Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.". Mol Med 17 (1-2): 113-25. doi:10.2119/molmed.2009.00153. PMC 3022978. PMID 20927486. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978/.