Ovarian small cell carcinoma of the hypercalcemic type
Ovarian small cell carcinoma of the hypercalcemic type, abbreviated OSSCHT, is a rare malignant ovarian tumour.
Small cell carcinoma, hypercalcemic type, and small cell carcinoma of the ovary, hypercalcemic type redirect here.
A proposed name of the entity is malignant rhabdoid tumour of the ovary, abbreviated MRTO.[1]
General
Microscopic
Features:[2]
- Small cell carcinoma.
- Follicle-like spaces.
DDx:
- Small cell carcinoma of the lung.
- Small cell carcinoma of the cervix.
- Sertoli-Leydig cell tumour.
- Juvenile granulosa cell tumour.
Images
www:
IHC
Features:[4]
See also
References
- ↑ Foulkes, WD.; Clarke, BA.; Hasselblatt, M.; Majewski, J.; Albrecht, S.; McCluggage, WG. (Jul 2014). "No small surprise - small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour.". J Pathol 233 (3): 209-14. doi:10.1002/path.4362. PMID 24752781.
- ↑ 2.0 2.1 Young, RH.; Oliva, E.; Scully, RE. (Nov 1994). "Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases.". Am J Surg Pathol 18 (11): 1102-16. PMID 7943531.
- ↑ 3.0 3.1 Witkowski L, Carrot-Zhang J, Albrecht S, et al. (May 2014). "Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type". Nat. Genet. 46 (5): 438–43. doi:10.1038/ng.2931. PMID 24658002.
- ↑ Carlson, JW.; Nucci, MR.; Brodsky, J.; Crum, CP.; Hirsch, MS. (Sep 2007). "Biomarker-assisted diagnosis of ovarian, cervical and pulmonary small cell carcinomas: the role of TTF-1, WT-1 and HPV analysis.". Histopathology 51 (3): 305-12. doi:10.1111/j.1365-2559.2007.02790.x. PMID 17727473.