Difference between revisions of "Intranodal palisaded myofibroblastoma"

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{{ Infobox diagnosis
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Name      = {{PAGENAME}}
| Image      = Intranodal palisaded myofibroblastoma - very high mag.jpg
| Image      = Intranodal palisaded myofibroblastoma - very high mag.jpg
| Width      = 200
| Caption    = IPM. [[H&E stain]].
| Caption    = IPM. [[H&E stain]].
| Micro      = Spindle cells with nuclear palisading, RBC extravasation.
| Micro      = spindle cells with nuclear palisading, RBC extravasation
| Subtypes  =
| Subtypes  =
| LMDDx      = [[Schwannoma]].
| LMDDx      = [[schwannoma]], [[leiomyoma]]
| Stains    =
| IHC        = SMA +ve, S-100 -ve.
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Prevalence = Very rare.
| Clinical  =
| ClinDDx    = [[Lymphoma]], metastatic carcinoma.
| SignsSx    = Mass lesion.
| Site      = [[Lymph node]].
}}
-->
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Intranodal palisaded myofibroblastoma - very high mag.jpg
| Width      =
| Caption    = IPM. [[H&E stain]].
| Micro      = Spindle cells with nuclear palisading, RBC extravasation.
| Subtypes  =
| LMDDx      = [[Schwannoma]].
| Stains    =  
| Stains    =  
| IHC        = SMA +ve, S-100 -ve.
| IHC        = SMA +ve, S-100 -ve.
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| Gross      =
| Gross      =
| Grossing  =
| Grossing  =
| Site      = [[Lymph node]].
| Site      = [[lymph node]].
| Signs      = Mass lesion.
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      = mass lesion
| Symptoms  =
| Symptoms  =
| Prevalence = Very rare.
| Prevalence = very rare.
| Bloodwork  =
| Bloodwork  =
| Rads      =
| Rads      =
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| Prognosis  =
| Prognosis  =
| Other      =
| Other      =
| ClinDDx    = [[Lymphoma]], metastatic carcinoma.
| ClinDDx    = [[lymphoma]], metastatic carcinoma.
}}
}}
'''Intranodal palisaded myofibroblastoma''', abbreviated '''IPM''', is a rare tumour that classically presents as an inguinal mass.<ref name=pmid17284119>{{Cite journal  | last1 = Nguyen | first1 = T. | last2 = Eltorky | first2 = MA. | title = Intranodal palisaded myofibroblastoma. | journal = Arch Pathol Lab Med | volume = 131 | issue = 2 | pages = 306-10 | month = Feb | year = 2007 | doi = 10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2 | PMID = 17284119 }}</ref>
'''Intranodal palisaded myofibroblastoma''', abbreviated '''IPM''', is a rare tumour that classically presents as an inguinal mass.<ref name=pmid17284119>{{Cite journal  | last1 = Nguyen | first1 = T. | last2 = Eltorky | first2 = MA. | title = Intranodal palisaded myofibroblastoma. | journal = Arch Pathol Lab Med | volume = 131 | issue = 2 | pages = 306-10 | month = Feb | year = 2007 | doi = 10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2 | PMID = 17284119 }}</ref>


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#Intracellular and extracellular fuchsinophilic bodies.
#Intracellular and extracellular fuchsinophilic bodies.
#*Smooth muscle actin +ve.
#*Smooth muscle actin +ve.
DDx:
*[[Schwannoma]].


Notes:
Notes:
*''Fuchsinophilic'' = affinity for the acid dye fuchsin.<ref>URL: [http://www.merriam-webster.com/medical/fuchsinophilic http://www.merriam-webster.com/medical/fuchsinophilic]. Accessed on: 3 October 2011.</ref>
*''Fuchsinophilic'' = affinity for the acid dye fuchsin.<ref>URL: [http://www.merriam-webster.com/medical/fuchsinophilic http://www.merriam-webster.com/medical/fuchsinophilic]. Accessed on: 3 October 2011.</ref>
**Image: [http://www.flickr.com/photos/53376324@N08/5387821397/in/photostream Fuchsinophilic material (flickr.com)] - red.
**Image: [http://www.flickr.com/photos/53376324@N08/5387821397/in/photostream Fuchsinophilic material (flickr.com)] - red.
DDx:<ref>{{Cite journal  | last1 = Sarma | first1 = NH. | last2 = Arora | first2 = KS. | last3 = Varalaxmi | first3 = KP. | title = Intranodal palisaded myofibroblastoma: a case report and an update on etiopathogenesis and differential diagnosis. | journal = J Cancer Res Ther | volume = 9 | issue = 2 | pages = 295-8 | month =  | year =  | doi = 10.4103/0973-1482.113395 | PMID = 23771380 }}</ref>
*[[Schwannoma]].
*[[Leiomyoma]].
*[[Leiomyosarcoma]].
*[[Malignant melanoma]].
*[[Kaposi sarcoma]].
*Metastatic carcinoma.


===Images===
===Images===
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Image: Intranodal palisaded myofibroblastoma - high mag.jpg | IPM - high mag. (WC/Nephron)
Image: Intranodal palisaded myofibroblastoma - high mag.jpg | IPM - high mag. (WC/Nephron)
Image: Intranodal palisaded myofibroblastoma - very high mag.jpg | IPM - very high mag. (WC/Nephron)
Image: Intranodal palisaded myofibroblastoma - very high mag.jpg | IPM - very high mag. (WC/Nephron)
Image: Intra-nodal palisaded myofibroblastoma.jpg | IPM - high mag. (WC)
</gallery>
</gallery>
www:
www:
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==IHC==
==IHC==
*SMA +ve.
*SMA +ve.
*Cyclin D1 +ve.
*Vimentin +ve.
*Cyclin D1 +ve/-ve.<ref name=pmid23771380>{{Cite journal  | last1 = Sarma | first1 = NH. | last2 = Arora | first2 = KS. | last3 = Varalaxmi | first3 = KP. | title = Intranodal palisaded myofibroblastoma: a case report and an update on etiopathogenesis and differential diagnosis. | journal = J Cancer Res Ther | volume = 9 | issue = 2 | pages = 295-8 | month =  | year =  | doi = 10.4103/0973-1482.113395 | PMID = 23771380 }}</ref>


Other:
Other:
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*Desmin -ve
*Desmin -ve
*Ki-67 - low.
*Ki-67 - low.
*HMB-45 -ve.


==See also==
==See also==
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