Difference between revisions of "Rhabdomyoma"
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==General== | ==General== | ||
*May be seen in the context of [[tuberous sclerosis]]. | *May be seen in the context of [[tuberous sclerosis]]. | ||
*Rare benign mesenchymal tumour - may be seen in the [[head and neck pathology|head and neck]].<ref name=pmid16133368/> | |||
==Gross== | ==Gross== | ||
Revision as of 14:34, 4 September 2017
Rhabdomyoma a benign muscle tumour. Often seen in the context of tuberous sclerosis.
General
- May be seen in the context of tuberous sclerosis.
- Rare benign mesenchymal tumour - may be seen in the head and neck.[1]
Gross
- Solid, white/tan colour.
Image:
Microscopic
Features - cardiac:[2]
- Spider cells:
- Large polygonal cells (~10-20x RBC diameter):
- Abundant cytoplasm filled with glycogen.
- Large polygonal cells (~10-20x RBC diameter):
Note:
- Fetal rhabdomyomas may have pseudoepitheliomatous hyperplasia.[1]
DDx:
Images
Rhabdomyoma - low mag. (WC)
Rhabdomyoma - intermed. mag. (WC)
Rhabdomyoma - high mag. (WC)
Rhabdomyoma - very high mag. (WC)
Rhabdomyoma - desmin - intermed. mag. (WC)
Rhabdomyoma - desmin - high mag. (WC)
www
IHC
Features:[1]
- Desmin +ve.
- Myogoblin +ve.
- Actin +ve.
- S-100 -ve.
- Positive in granular cell tumour and hiberoma.
See also
References
- ↑ 1.0 1.1 1.2 Hansen, T.; Katenkamp, D. (Nov 2005). "Rhabdomyoma of the head and neck: morphology and differential diagnosis.". Virchows Arch 447 (5): 849-54. doi:10.1007/s00428-005-0038-8. PMID 16133368.
- ↑ URL: http://www.brown.edu/Courses/Digital_Path/systemic_path/cardio/rhabdomyoma.html. Accessed on: 19 October 2011.