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Difference between revisions of "Case 86"
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[Chromophobe renal cell carcinoma]], eosinophilic variant</center>}} | {{hidden|Diagnosis|<center>[[Chromophobe renal cell carcinoma]], eosinophilic variant</center> | ||
<br>Comment:<br> | |||
The main differential diagnosis is [[renal oncocytoma]]. [[Hale's colloidal iron]] (blue in ChRCC), and CK7 (strong membranous in ChRCC versus weak/patchy in oncocytoma) are quite useful. | |||
Morphologically, ChRCC typically has perinuclear halos (may be focal), frequent binucleation and wrinkled nuclear membranes (raisinoid nuclei).<ref name=pmid9844591>{{Cite journal | last1 = Tickoo | first1 = SK. | last2 = Amin | first2 = MB. | title = Discriminant nuclear features of renal oncocytoma and chromophobe renal cell carcinoma. Analysis of their potential utility in the differential diagnosis. | journal = Am J Clin Pathol | volume = 110 | issue = 6 | pages = 782-7 | month = Dec | year = 1998 | doi = | PMID = 9844591 }}</ref> | |||
===Reference=== | |||
{{Reflist|1}} | |||
}} | |||
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