Tumour regression - Revision history

Michael at 18:48, 5 May 2025

2025-05-05T18:48:44Z

← Older revision		Revision as of 18:48, 5 May 2025
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	{{Main\|Ovarian carcinoma}}		{{Main\|Ovarian carcinoma}}
	This has been examined by McCluggage ''et al.''<ref name=pmid11825920>{{Cite journal \| last1 = McCluggage \| first1 = WG. \| last2 = Lyness \| first2 = RW. \| last3 = Atkinson \| first3 = RJ. \| last4 = Dobbs \| first4 = SP. \| last5 = Harley \| first5 = I. \| last6 = McClelland \| first6 = HR. \| last7 = Price \| first7 = JH. \| title = Morphological effects of chemotherapy on ovarian carcinoma. \| journal = J Clin Pathol \| volume = 55 \| issue = 1 \| pages = 27-31 \| month = Jan \| year = 2002 \| doi = \| PMID = 11825920 }}</ref>		This has been examined by McCluggage ''et al.''<ref name=pmid11825920>{{Cite journal \| last1 = McCluggage \| first1 = WG. \| last2 = Lyness \| first2 = RW. \| last3 = Atkinson \| first3 = RJ. \| last4 = Dobbs \| first4 = SP. \| last5 = Harley \| first5 = I. \| last6 = McClelland \| first6 = HR. \| last7 = Price \| first7 = JH. \| title = Morphological effects of chemotherapy on ovarian carcinoma. \| journal = J Clin Pathol \| volume = 55 \| issue = 1 \| pages = 27-31 \| month = Jan \| year = 2002 \| doi = \| PMID = 11825920 }}</ref>

			==See also==
			*[[Neoadjuvant therapy]].

	==References==		==References==

Michael: /* Esophageal carcinoma */

2021-03-14T17:57:54Z

Esophageal carcinoma

← Older revision		Revision as of 17:57, 14 March 2021
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	====Esophageal carcinoma====		====Esophageal carcinoma====
	*The three tier system from Ryan ''et al'' for colorectal cancer has been applied to esophageal carcinomas.<ref>{{cite journal \|authors=Takeda FR, Tustumi F, de Almeida Obregon C, Yogolare GG, Navarro YP, Segatelli V, Sallum RAA, Junior UR, Cecconello I \|title=Prognostic Value of Tumor Regression Grade Based on Ryan Score in Squamous Cell Carcinoma and Adenocarcinoma of Esophagus \|journal=Ann Surg Oncol \|volume=27 \|issue=4 \|pages=1241–1247 \|date=April 2020 \|pmid=31664618 \|doi=10.1245/s10434-019-07967-8 \|url=}}</ref>		*The three tier system from Ryan ''et al.'' for colorectal cancer has been applied to esophageal carcinomas.<ref>{{cite journal \|authors=Takeda FR, Tustumi F, de Almeida Obregon C, Yogolare GG, Navarro YP, Segatelli V, Sallum RAA, Junior UR, Cecconello I \|title=Prognostic Value of Tumor Regression Grade Based on Ryan Score in Squamous Cell Carcinoma and Adenocarcinoma of Esophagus \|journal=Ann Surg Oncol \|volume=27 \|issue=4 \|pages=1241–1247 \|date=April 2020 \|pmid=31664618 \|doi=10.1245/s10434-019-07967-8 \|url=}}</ref>

	====Ovarian carcinoma====		====Ovarian carcinoma====

Michael: /* Grading of tumour regression */

2021-03-14T17:57:42Z

Grading of tumour regression

← Older revision		Revision as of 17:57, 14 March 2021
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	{{Main\|Colorectal carcinoma}}		{{Main\|Colorectal carcinoma}}
	There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>		There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>

			====Esophageal carcinoma====
			*The three tier system from Ryan ''et al'' for colorectal cancer has been applied to esophageal carcinomas.<ref>{{cite journal \|authors=Takeda FR, Tustumi F, de Almeida Obregon C, Yogolare GG, Navarro YP, Segatelli V, Sallum RAA, Junior UR, Cecconello I \|title=Prognostic Value of Tumor Regression Grade Based on Ryan Score in Squamous Cell Carcinoma and Adenocarcinoma of Esophagus \|journal=Ann Surg Oncol \|volume=27 \|issue=4 \|pages=1241–1247 \|date=April 2020 \|pmid=31664618 \|doi=10.1245/s10434-019-07967-8 \|url=}}</ref>

	====Ovarian carcinoma====		====Ovarian carcinoma====

Michael at 14:46, 7 November 2012

2012-11-07T14:46:01Z

← Older revision		Revision as of 14:46, 7 November 2012
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	'''Tumour regression''' can occur as a consequence of treatment ~~or sporadically~~.		'''Tumour regression''' can occur (1) sporadically, or (2) as a consequence of treatment (treatment response).

	==Sporadic tumour regression==		==Sporadic tumour regression==

Michael: /* Microscopic */ redirect

2012-11-07T14:42:19Z

Microscopic: redirect

← Older revision		Revision as of 14:42, 7 November 2012
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	===Grading of tumour regression===		===Grading of tumour regression===
			====Colorectal carcinoma====
			{{Main\|Colorectal carcinoma}}
	There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>		There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>

			====Ovarian carcinoma====
			{{Main\|Ovarian carcinoma}}
			This has been examined by McCluggage ''et al.''<ref name=pmid11825920>{{Cite journal \| last1 = McCluggage \| first1 = WG. \| last2 = Lyness \| first2 = RW. \| last3 = Atkinson \| first3 = RJ. \| last4 = Dobbs \| first4 = SP. \| last5 = Harley \| first5 = I. \| last6 = McClelland \| first6 = HR. \| last7 = Price \| first7 = JH. \| title = Morphological effects of chemotherapy on ovarian carcinoma. \| journal = J Clin Pathol \| volume = 55 \| issue = 1 \| pages = 27-31 \| month = Jan \| year = 2002 \| doi = \| PMID = 11825920 }}</ref>

	==References==		==References==

Michael: /* Microscopic */

2012-11-04T21:32:32Z

Microscopic

← Older revision		Revision as of 21:32, 4 November 2012
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	*+/-Inflammation.		*+/-Inflammation.
	*+/-Histiocytes.		*+/-Histiocytes.

			Note:
			*There are specific criteria for ''[[malignant melanoma]]''.

	===Grading of tumour regression===		===Grading of tumour regression===
	There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>		There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>

	~~Note:~~
	*There are specific criteria for ''[[malignant melanoma]]''.

	==References==		==References==

Michael: /* Microscopic */

2012-11-04T21:30:56Z

Microscopic

← Older revision		Revision as of 21:30, 4 November 2012
Line 18:		Line 18:
	*+/-Mucin.		*+/-Mucin.
	*+/-Inflammation.		*+/-Inflammation.
			*+/-Histiocytes.

	===Grading of tumour regression===		===Grading of tumour regression===

Michael: /* Grading of tumour regression */

2012-11-04T21:30:08Z

Grading of tumour regression

← Older revision		Revision as of 21:30, 4 November 2012
Line 20:		Line 20:

	===Grading of tumour regression===		===Grading of tumour regression===
	There is a three tiered regression grading system by Ryan ''et al''.<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>		There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]].<ref name=pmid16045774>{{Cite journal \| last1 = Ryan \| first1 = R. \| last2 = Gibbons \| first2 = D. \| last3 = Hyland \| first3 = JM. \| last4 = Treanor \| first4 = D. \| last5 = White \| first5 = A. \| last6 = Mulcahy \| first6 = HE. \| last7 = O'Donoghue \| first7 = DP. \| last8 = Moriarty \| first8 = M. \| last9 = Fennelly \| first9 = D. \| title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. \| journal = Histopathology \| volume = 47 \| issue = 2 \| pages = 141-6 \| month = Aug \| year = 2005 \| doi = 10.1111/j.1365-2559.2005.02176.x \| PMID = 16045774 }}</ref>

	Note:		Note:

Michael: /* Sporadic tumour regression */ rm dup ref

2012-08-28T01:52:12Z

Sporadic tumour regression: rm dup ref

← Older revision		Revision as of 01:52, 28 August 2012
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	Note:		Note:
	*Melanocytic lesions in general, ''not'' only melanoma, may regress.<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref><ref name=pmid21029398>{{Cite journal \| last1 = Speeckaert \| first1 = R. \| last2 = van Geel \| first2 = N. \| last3 = Vermaelen \| first3 = KV. \| last4 = Lambert \| first4 = J. \| last5 = Van Gele \| first5 = M. \| last6 = Speeckaert \| first6 = MM. \| last7 = Brochez \| first7 = L. \| title = Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy. \| journal = Pigment Cell Melanoma Res \| volume = 24 \| issue = 2 \| pages = 334-44 \| month = Apr \| year = 2011 \| doi = 10.1111/j.1755-148X.2010.00799.x \| PMID = 21029398 ~~}}</ref><ref name=Ref_Derm476>{{Ref Derm\|476~~}}</ref>		*Melanocytic lesions in general, ''not'' only melanoma, may regress.<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref><ref name=pmid21029398>{{Cite journal \| last1 = Speeckaert \| first1 = R. \| last2 = van Geel \| first2 = N. \| last3 = Vermaelen \| first3 = KV. \| last4 = Lambert \| first4 = J. \| last5 = Van Gele \| first5 = M. \| last6 = Speeckaert \| first6 = MM. \| last7 = Brochez \| first7 = L. \| title = Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy. \| journal = Pigment Cell Melanoma Res \| volume = 24 \| issue = 2 \| pages = 334-44 \| month = Apr \| year = 2011 \| doi = 10.1111/j.1755-148X.2010.00799.x \| PMID = 21029398 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Sporadic tumour regression */ more

2012-08-28T01:51:54Z

Sporadic tumour regression: more

← Older revision		Revision as of 01:51, 28 August 2012
Line 9:		Line 9:
	May occur in:		May occur in:
	*[[Basal cell carcinoma]].<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref>		*[[Basal cell carcinoma]].<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref>
	*[[Melanocytic ~~nevi]]~~.<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref>
			Note:
			*Melanocytic lesions in general, ''not'' only melanoma, may regress.<ref name=Ref_Derm476>{{Ref Derm\|476}}</ref><ref name=pmid21029398>{{Cite journal \| last1 = Speeckaert \| first1 = R. \| last2 = van Geel \| first2 = N. \| last3 = Vermaelen \| first3 = KV. \| last4 = Lambert \| first4 = J. \| last5 = Van Gele \| first5 = M. \| last6 = Speeckaert \| first6 = MM. \| last7 = Brochez \| first7 = L. \| title = Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy. \| journal = Pigment Cell Melanoma Res \| volume = 24 \| issue = 2 \| pages = 334-44 \| month = Apr \| year = 2011 \| doi = 10.1111/j.1755-148X.2010.00799.x \| PMID = 21029398 }}</ref><ref name=Ref_Derm476>{{Ref Derm\|476}}</ref>

	==Microscopic==		==Microscopic==