Reactive changes - Revision history

Michael: /* See also */

2016-07-31T18:28:14Z

Michael at 07:40, 31 December 2014

2014-12-31T07:40:29Z

← Older revision		Revision as of 07:40, 31 December 2014
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	# Inflammation.		# Inflammation.
	# Nuclear changes compatible with inflammation.		# Nuclear changes compatible with inflammation.
	# The absence of both neoplasia ''and'' the ~~suspicious~~ of neoplasia, i.e. it implies benignancy.		# The absence of both neoplasia ''and'' the suspicion of neoplasia, i.e. it implies benignancy.

	'''Reactive inflammatory changes''' and '''inflammatory changes''' can be considered synonyms.		'''Reactive inflammatory changes''' and '''inflammatory changes''' can be considered synonyms.

Michael: /* Microscopic */

2014-12-31T07:31:24Z

Microscopic

← Older revision		Revision as of 07:31, 31 December 2014
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	*Inflammation - any type (e.g. [[neutrophil\|neutrophilic]], [[plasma cells\|plasmacytic]], lymphoplasmacytic).		*Inflammation - any type (e.g. [[neutrophil\|neutrophilic]], [[plasma cells\|plasmacytic]], lymphoplasmacytic).
	*+/-Proliferation (e.g. mitotic figures) or changes suggestive of proliferation (e.g. hyperplasia).		*+/-Proliferation (e.g. mitotic figures) or changes suggestive of proliferation (e.g. hyperplasia).

			Notes:
			*Cytoplasmic changes may be present.

	DDx:		DDx:

Michael: /* Microscopic */

2014-12-31T07:28:46Z

Microscopic

← Older revision		Revision as of 07:28, 31 December 2014
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	**Terminology dependent on the anatomical site, e.g. [[indefinite for dysplasia]], [[ASCUS]], [[ASAP]].		**Terminology dependent on the anatomical site, e.g. [[indefinite for dysplasia]], [[ASCUS]], [[ASAP]].
	*[[Nuclear atypia]].		*[[Nuclear atypia]].
	**This is often qualified as it may represent neoplastic process or a benign process ~~dependent on the context~~.		**This is often qualified as it may represent a neoplastic process or a benign process.
	**Common qualifiers:		**Common qualifiers:
	***Worrisome lesions: "cannot exclude dysplasia", "suspicious for malignancy".		***Worrisome lesions: "... cannot exclude dysplasia", "... cannot exclude malignancy", "... suspicious for malignancy".
	***Suspected to be benign: "favour benign".		***Suspected to be benign: "... favour benign".
	*[[Malignancy]].		*[[Malignancy]].

Michael at 07:25, 31 December 2014

2014-12-31T07:25:55Z

← Older revision		Revision as of 07:25, 31 December 2014
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	# Inflammation.		# Inflammation.
	# Nuclear changes compatible with inflammation.		# Nuclear changes compatible with inflammation.
	# The absence of both neoplasia and the suspicious of neoplasia, i.e. benignancy.		# The absence of both neoplasia ''and'' the suspicious of neoplasia, i.e. it implies benignancy.

	'''Reactive inflammatory changes''' and '''inflammatory changes''' can be considered synonyms.		'''Reactive inflammatory changes''' and '''inflammatory changes''' can be considered synonyms.

Michael at 07:25, 31 December 2014

2014-12-31T07:25:01Z

← Older revision		Revision as of 07:25, 31 December 2014
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	DDx:		DDx:
			*Normal.
	*[[Waffle diagnosis]] - nuclear changes of unknown significance.		*[[Waffle diagnosis]] - nuclear changes of unknown significance.
	**Terminology dependent on the anatomical site, e.g. [[indefinite for dysplasia]], [[ASCUS]], [[ASAP]].		**Terminology dependent on the anatomical site, e.g. [[indefinite for dysplasia]], [[ASCUS]], [[ASAP]].

Michael: /* Microscopic */

2014-12-31T07:23:01Z

Microscopic

← Older revision		Revision as of 07:23, 31 December 2014
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	DDx:		DDx:
	*[[Waffle diagnosis]] ~~(e.g. [[indefinite for dysplasia]])~~ - nuclear changes of unknown significance.		*[[Waffle diagnosis]] - nuclear changes of unknown significance.
	**Terminology dependent on the anatomical site.		**Terminology dependent on the anatomical site, e.g. [[indefinite for dysplasia]], [[ASCUS]], [[ASAP]].
	*[[Nuclear atypia]].		*[[Nuclear atypia]].
	**This is often qualified as it may represent neoplastic process or a benign process dependent on the context.		**This is often qualified as it may represent neoplastic process or a benign process dependent on the context.

Michael: fix

2014-12-31T07:21:20Z

fix

← Older revision		Revision as of 07:21, 31 December 2014
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	# The absence of both neoplasia and the suspicious of neoplasia, i.e. benignancy.		# The absence of both neoplasia and the suspicious of neoplasia, i.e. benignancy.

	'''Reactive inflammatory changes''' and ''inflammatory changes''' can be considered synonyms.		'''Reactive inflammatory changes''' and '''inflammatory changes''' can be considered synonyms.

	==General==		==General==

Michael at 07:20, 31 December 2014

2014-12-31T07:20:59Z

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	~~:''Reactive inflammatory changes'' and ''inflammatory changes'' redirect here.~~
	'''Reactive changes''' is a commonly used term in [[pathology]] that implies:		'''Reactive changes''' is a commonly used term in [[pathology]] that implies:
	# Inflammation.		# Inflammation.
	# Nuclear changes compatible with inflammation.		# Nuclear changes compatible with inflammation.
			# The absence of both neoplasia and the suspicious of neoplasia, i.e. benignancy.

			'''Reactive inflammatory changes''' and ''inflammatory changes''' can be considered synonyms.

	==General==		==General==
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	*Inflammatory processes.		*Inflammatory processes.
	*Repair.		*Repair.
	*Neoplastic processes.		*Neoplastic processes, i.e. pre-cancerous conditions (e.g. dysplasia) and [[cancer]].

	Significance of nuclear changes in inflammation:		Significance of nuclear changes in inflammation:
	*The line between a reactive process and a neoplastic process may be fuzzy, i.e. it may be very difficult to be certain whether something is benign or malignant.		*The line between a reactive process and a neoplastic process may be fuzzy, i.e. it may be very difficult to be certain whether something is benign or [[malignant]].

	Consequence:		Consequence:
	*In the context of inflammation, nuclear changes are typically present and the threshold for calling suspicious or malignancy is typically higher.		*In the context of inflammation, nuclear changes are typically present and the threshold for calling ''suspicious for malignancy'' or ''[[malignancy]]'' is typically higher.

	==Microscopic==		==Microscopic==

Michael at 07:13, 31 December 2014

2014-12-31T07:13:40Z

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	**Prominent [[nucleoli]].		**Prominent [[nucleoli]].
	*Inflammation - any type (e.g. [[neutrophil\|neutrophilic]], [[plasma cells\|plasmacytic]], lymphoplasmacytic).		*Inflammation - any type (e.g. [[neutrophil\|neutrophilic]], [[plasma cells\|plasmacytic]], lymphoplasmacytic).
			*+/-Proliferation (e.g. mitotic figures) or changes suggestive of proliferation (e.g. hyperplasia).

	DDx:		DDx:

← Older revision		Revision as of 18:28, 31 July 2016
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	*[[NC ratio]].		*[[NC ratio]].
	*[[Reactive squamous epithelium of the uterine cervix]].		*[[Reactive squamous epithelium of the uterine cervix]].
			*[[Reactive astrocytes]].

	[[Category:Stuff]]		[[Category:Stuff]]