Pyloric gland adenoma - Revision history

Michael: /* Microscopic */

2022-09-15T17:53:44Z

Microscopic

← Older revision		Revision as of 17:53, 15 September 2022
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	===Images===		===Images===
	*[http://www.revistagastroenterologiamexico.org/imatges/288/288v75n03/grande/288v75n03-13156080fig2.jpg Pyloric gland adenoma (revistagastroenterologiamexico.org)].<ref>URL: [http://www.revistagastroenterologiamexico.org/es/pyloric-gland-adenoma-case-report/articulo/13156080/ http://www.revistagastroenterologiamexico.org/es/pyloric-gland-adenoma-case-report/articulo/13156080/]. Accessed on: 6 September 2014.</ref>
	*[http://www.flickriver.com/photos/lunarcaustic/3488308419/ Tubulare adenoma, pyloric gland-type (flickriver.com)].		*[http://www.flickriver.com/photos/lunarcaustic/3488308419/ Tubulare adenoma, pyloric gland-type (flickriver.com)].

	==IHC==		==IHC==
	*Ki-67 high.		*Ki-67 high.

Michael at 06:16, 6 September 2014

2014-09-06T06:16:32Z

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	*[[Adenocarcinoma of the stomach]], well-differentiated.		*[[Adenocarcinoma of the stomach]], well-differentiated.

			===Images===
			*[http://www.revistagastroenterologiamexico.org/imatges/288/288v75n03/grande/288v75n03-13156080fig2.jpg Pyloric gland adenoma (revistagastroenterologiamexico.org)].<ref>URL: [http://www.revistagastroenterologiamexico.org/es/pyloric-gland-adenoma-case-report/articulo/13156080/ http://www.revistagastroenterologiamexico.org/es/pyloric-gland-adenoma-case-report/articulo/13156080/]. Accessed on: 6 September 2014.</ref>
			*[http://www.flickriver.com/photos/lunarcaustic/3488308419/ Tubulare adenoma, pyloric gland-type (flickriver.com)].
	==IHC==		==IHC==
	*Ki-67 high.		*Ki-67 high.

Michael: +dx cat.

2014-09-06T05:41:21Z

+dx cat.

← Older revision		Revision as of 05:41, 6 September 2014
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	[[Category:Gastrointestinal pathology]]		[[Category:Gastrointestinal pathology]]
			[[Category:Diagnosis]]

Michael at 05:24, 6 September 2014

2014-09-06T05:24:39Z

← Older revision		Revision as of 05:24, 6 September 2014
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	==Microscopic==		==Microscopic==
	Features:		Features:<ref name=pmid18830123/>
	*Round mildly irregular foveolar-type glands with:		*Round mildly irregular foveolar-type glands with:
	**Nuclei without dysplasia (round and basally located nuclei) or with dysplasia.		**Nuclei without dysplasia (round and basally located nuclei) or with dysplasia.

Michael at 05:23, 6 September 2014

2014-09-06T05:23:57Z

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	**Negative in foveolar-type gastric adenomas.		**Negative in foveolar-type gastric adenomas.
	*MUC5AC +ve.<ref name=pmid18830123/>		*MUC5AC +ve.<ref name=pmid18830123/>

			==See also==
			*[[Autoimmune gastritis]].

	==References==		==References==

Michael at 05:23, 6 September 2014

2014-09-06T05:23:31Z

← Older revision		Revision as of 05:23, 6 September 2014
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	\| Caption =		\| Caption =
	\| Synonyms =		\| Synonyms =
	\| Micro = ~~round mildly irregular~~ foveolar-type glands with ~~round~~, ~~basal, bland~~ nuclei		\| Micro = foveolar-type glands with eosinophilic (or clear) cytoplasm, nuclei with or without dysplasia
	\| Subtypes =		\| Subtypes =
	\| LMDDx = foveolar-type [[gastric adenoma]], well-differentiated [[gastric adenocarcinoma]]		\| LMDDx = foveolar-type [[gastric adenoma]], well-differentiated [[gastric adenocarcinoma]]
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	\| Prognosis = benign		\| Prognosis = benign
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx = other [[GI polyps\|polyps]]
	\| Tx =		\| Tx = excision
	}}		}}
	'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.		'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.

Michael at 05:21, 6 September 2014

2014-09-06T05:21:52Z

← Older revision		Revision as of 05:21, 6 September 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = round mildly irregular foveolar-type glands with round, basal, bland nuclei
			\| Subtypes =
			\| LMDDx = foveolar-type [[gastric adenoma]], well-differentiated [[gastric adenocarcinoma]]
			\| Stains =
			\| IHC = MUC6 +ve, MUC5AC +ve, Ki-67 high
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[stomach]], [[duodenum]], [[gallbladder]], others
			\| Assdx = well-differentiated [[gastric adenocarcinoma]], [[autoimmune gastritis]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy = polyp
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.		'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.

	==General==		==General==
	*~~Less than~~ 3% of gastric polyps.<ref name=pmid16506593>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Vogel \| first2 = C. \| last3 = Kushima \| first3 = R. \| last4 = Borchard \| first4 = F. \| last5 = Stolte \| first5 = M. \| title = Pyloric gland adenoma-- how to diagnose? \| journal = Cesk Patol \| volume = 42 \| issue = 1 \| pages = 4-7 \| month = Jan \| year = 2006 \| doi = \| PMID = 16506593 }}</ref>		*Approximately 3% of gastric polyps.<ref name=pmid16506593>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Vogel \| first2 = C. \| last3 = Kushima \| first3 = R. \| last4 = Borchard \| first4 = F. \| last5 = Stolte \| first5 = M. \| title = Pyloric gland adenoma-- how to diagnose? \| journal = Cesk Patol \| volume = 42 \| issue = 1 \| pages = 4-7 \| month = Jan \| year = 2006 \| doi = \| PMID = 16506593 }}</ref>
	*Associated with [[autoimmune gastritis]].<ref>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Montgomery \| first2 = EA. \| title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! \| journal = J Clin Pathol \| volume = \| issue = \| pages = \| month = Aug \| year = 2014 \| doi = 10.1136/jclinpath-2014-202553 \| PMID = 25092673 }}</ref>		*Associated with [[autoimmune gastritis]].<ref>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Montgomery \| first2 = EA. \| title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! \| journal = J Clin Pathol \| volume = \| issue = \| pages = \| month = Aug \| year = 2014 \| doi = 10.1136/jclinpath-2014-202553 \| PMID = 25092673 }}</ref>
			*More often seen in women as with autoimmune gastritis.
			*Associated with [[gastric adenocarcinoma]].

	==Microscopic==		==Microscopic==
			Features:
			*Round mildly irregular foveolar-type glands with:
			**Nuclei without dysplasia (round and basally located nuclei) or with dysplasia.
			**Moderate eosinophilic (or clear) cytoplasm.

	DDx:		DDx:

Michael at 04:56, 6 September 2014

2014-09-06T04:56:38Z

← Older revision		Revision as of 04:56, 6 September 2014
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	'''Pyloric gland adenoma''' is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.		'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology\|gastrointestinal]] lesion.

	==General==		==General==
	*Less than 3% of gastric polyps.<ref>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Vogel \| first2 = C. \| last3 = Kushima \| first3 = R. \| last4 = Borchard \| first4 = F. \| last5 = Stolte \| first5 = M. \| title = Pyloric gland adenoma-- how to diagnose? \| journal = Cesk Patol \| volume = 42 \| issue = 1 \| pages = 4-7 \| month = Jan \| year = 2006 \| doi = \| PMID = 16506593 }}</ref>		*Less than 3% of gastric polyps.<ref name=pmid16506593>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Vogel \| first2 = C. \| last3 = Kushima \| first3 = R. \| last4 = Borchard \| first4 = F. \| last5 = Stolte \| first5 = M. \| title = Pyloric gland adenoma-- how to diagnose? \| journal = Cesk Patol \| volume = 42 \| issue = 1 \| pages = 4-7 \| month = Jan \| year = 2006 \| doi = \| PMID = 16506593 }}</ref>
	*Associated with [[autoimmune gastritis]].<ref>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Montgomery \| first2 = EA. \| title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! \| journal = J Clin Pathol \| volume = \| issue = \| pages = \| month = Aug \| year = 2014 \| doi = 10.1136/jclinpath-2014-202553 \| PMID = 25092673 }}</ref>		*Associated with [[autoimmune gastritis]].<ref>{{Cite journal \| last1 = Vieth \| first1 = M. \| last2 = Montgomery \| first2 = EA. \| title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! \| journal = J Clin Pathol \| volume = \| issue = \| pages = \| month = Aug \| year = 2014 \| doi = 10.1136/jclinpath-2014-202553 \| PMID = 25092673 }}</ref>

Michael at 04:55, 6 September 2014

2014-09-06T04:55:18Z

← Older revision		Revision as of 04:55, 6 September 2014
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	DDx:		DDx:
	*[[Gastric adenoma]].		*[[Gastric adenoma]], foveolar-type.
	*[[Adenocarcinoma of the stomach]].		*[[Adenocarcinoma of the stomach]], well-differentiated.

	==IHC==		==IHC==

Michael at 04:54, 6 September 2014

2014-09-06T04:54:00Z

← Older revision		Revision as of 04:54, 6 September 2014
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	==IHC==		==IHC==
	*Ki-67 high.		*Ki-67 high.
	*MUC6 +ve.{{~~fact~~}}		*MUC6 +ve.<ref name=pmid18830123>{{Cite journal \| last1 = Chen \| first1 = ZM. \| last2 = Scudiere \| first2 = JR. \| last3 = Abraham \| first3 = SC. \| last4 = Montgomery \| first4 = E. \| title = Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 2 \| pages = 186-93 \| month = Feb \| year = 2009 \| doi = 10.1097/PAS.0b013e31817d7ff4 \| PMID = 18830123 }}</ref>
			**Negative in foveolar-type gastric adenomas.
			*MUC5AC +ve.<ref name=pmid18830123/>

	==References==		==References==