Multiple sclerosis - Revision history

Michael: /* Microscopic */ +images

2014-11-15T06:34:26Z

Microscopic: +images

← Older revision		Revision as of 06:34, 15 November 2014
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	*[[Diffuse astrocytoma]].		*[[Diffuse astrocytoma]].

	Images:		===Images===
			<gallery>
			Image: MS_Demyelinisation_CD68_10xv2.jpg \| Demyelination in MS - CD68 stain. (WC/Marvin 101)
			Image: MS Demyelinisation KB 10x.jpg \| Demyelination in MS - KB stain. (WC/Marvin 101)
			</gallery>
			www:
	*[http://path.upmc.edu/cases/case79.html Multiple sclerosis masquerading as a diffuse astrocytoma - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case79.html Multiple sclerosis masquerading as a diffuse astrocytoma - several images (upmc.edu)].
	*[http://path.upmc.edu/cases/case636.html Tumefactive multiple sclerosis - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case636.html Tumefactive multiple sclerosis - several images (upmc.edu)].

Michael: split-out

2014-11-15T06:06:07Z

split-out

← Older revision		Revision as of 06:06, 15 November 2014
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	#~~redirect~~ [[Neuropathology~~#Multiple_sclerosis~~]]		'''Multiple sclerosis''', abbreviated '''MS''', is a chronic inflammatory condition of the central nervous system.

			==General==
			*A bread 'n butter disease of neurology in Canada.

			Clinical:
			*CSF: oligoclonal bands of immunoglobulin.<ref>{{Ref PBoD8\|1311}}</ref>

			Classification of MS lesions:
			*Early active.
			*Inactive.
			*Early remyelinating.
			*Late remyelinating.

			==Radiologic/Gross==
			Features:<ref>URL: [http://library.med.utah.edu/kw/ms/path.html http://library.med.utah.edu/kw/ms/path.html]. Accessed on: 12 July 2010.</ref>
			*White matter lesions.
			**Cerebrum (classically): periventricular distribution.
			**Optic nerves (optic neuritis) - classic presentation.

			==Microscopic==
			Features:<ref>URL: [http://library.med.utah.edu/kw/ms/path.html http://library.med.utah.edu/kw/ms/path.html]. Accessed on: 12 July 2010.</ref>
			*Perivascular inflammation.
			**Esp. lymphocytes.
			*Demyelination.
			**Subcortical myelinated fibers are often spared.

			Chronic lesions - specific features:<ref>{{Ref APBR\|425 Q43}}</ref>
			#Macrophages.
			#Astrocyte enlargement.

			DDx:
			*[[ADEM]].
			*[[Neuromyelitis optica]].
			*[[Lymphoma]].
			*[[Diffuse astrocytoma]].

			Images:
			*[http://path.upmc.edu/cases/case79.html Multiple sclerosis masquerading as a diffuse astrocytoma - several images (upmc.edu)].
			*[http://path.upmc.edu/cases/case636.html Tumefactive multiple sclerosis - several images (upmc.edu)].

			==IHC==
			*HAM-56 - macrophages.
			*CD8 - lymphocytes.

			==See also==
			*[[Neuropathology]].

			==References==
			{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology]]

Michael: redirect w/ cat

2011-11-26T22:37:35Z

redirect w/ cat

← Older revision		Revision as of 22:37, 26 November 2011
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	#redirect [[Neuropathology#Multiple_sclerosis]]		#redirect [[Neuropathology#Multiple_sclerosis]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-03-30T03:06:26Z

redirect for now

New page

#redirect [[Neuropathology#Multiple_sclerosis]]