Lymphocytic colitis - Revision history

Michael: /* Microscopic */

2016-05-25T14:29:41Z

Microscopic

← Older revision		Revision as of 14:29, 25 May 2016
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	==Microscopic==		==Microscopic==
	Features:		Features:
	*Lots of intraepithelial lymphocytes (>=20/100 lymphocytes/surface epithelial cells<ref name=pmid19109861>{{cite journal \|author=Tysk C, Bohr J, Nyhlin N, Wickbom A, Eriksson S \|title=Diagnosis and management of microscopic colitis \|journal=World J. Gastroenterol. \|volume=14 \|issue=48 \|pages=7280-8 \|year=2008 \|month=December \|pmid=19109861 \| PMC = 2778111 \|doi= \|url=http://www.wjgnet.com/1007-9327/14/7280.asp}}</ref>) and		*Lots of [[intraepithelial lymphocytes]] (>=20/100 lymphocytes/surface epithelial cells<ref name=pmid19109861>{{cite journal \|author=Tysk C, Bohr J, Nyhlin N, Wickbom A, Eriksson S \|title=Diagnosis and management of microscopic colitis \|journal=World J. Gastroenterol. \|volume=14 \|issue=48 \|pages=7280-8 \|year=2008 \|month=December \|pmid=19109861 \| PMC = 2778111 \|doi= \|url=http://www.wjgnet.com/1007-9327/14/7280.asp}}</ref>) and
	*Lymphocytes in the lamina propria.		*Lymphocytes in the lamina propria.

Michael: tweak

2016-03-19T04:37:38Z

tweak

← Older revision		Revision as of 04:37, 19 March 2016
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	**NSAIDs - posulated association/weak association,		**NSAIDs - posulated association/weak association,
	**SSRIs (used primarily for depression) - moderate association, dependent on specific drug.		**SSRIs (used primarily for depression) - moderate association, dependent on specific drug.
	*Associated with autoimmune disorders - [[celiac disease]], [[diabetes mellitus]], [[thyroid]] disorders and [[arthritis]].<ref name=pmid19109861>{{cite journal \|author=Tysk C, Bohr J, Nyhlin N, Wickbom A, Eriksson S \|title=Diagnosis and management of microscopic colitis \|journal=World J. Gastroenterol. \|volume=14 \|issue=48 \|pages=7280-8 \|year=2008 \|month=December \|pmid=19109861 \|doi= \|url=http://www.wjgnet.com/1007-9327/14/7280.asp}}</ref>		*Associated with autoimmune disorders - [[celiac disease]], [[diabetes mellitus]], [[thyroid]] disorders and [[arthritis]].<ref name=pmid19109861>{{cite journal \|author=Tysk C, Bohr J, Nyhlin N, Wickbom A, Eriksson S \|title=Diagnosis and management of microscopic colitis \|journal=World J. Gastroenterol. \|volume=14 \|issue=48 \|pages=7280-8 \|year=2008 \|month=December \|pmid=19109861 \| PMC = 2778111 \|doi= \|url=http://www.wjgnet.com/1007-9327/14/7280.asp}}</ref>
	*No increased risk of colorectal carcinoma.<ref name=pmid19109861/>		*No increased risk of colorectal carcinoma.<ref name=pmid19109861/>

Michael: /* See also */

2016-03-19T04:34:02Z

Michael at 04:44, 25 January 2015

2015-01-25T04:44:48Z

← Older revision		Revision as of 04:44, 25 January 2015
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	'''Lymphocytic colitis''', abbreviated '''LC''', is a type of [[microscopic colitis]]. It has a characteristic clinical presentation and no apparent endoscopic changes.		'''Lymphocytic colitis''', abbreviated '''LC''', is a type of [[microscopic colitis]]. It has a characteristic clinical presentation and no apparent endoscopic changes.

	''Lymphocytic proctitis'' redirects to here.		''Lymphocytic proctitis'' redirects here.

	==General==		==General==

Michael at 04:44, 25 January 2015

2015-01-25T04:44:16Z

← Older revision		Revision as of 04:44, 25 January 2015
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	}}		}}
	'''Lymphocytic colitis''', abbreviated '''LC''', is a type of [[microscopic colitis]]. It has a characteristic clinical presentation and no apparent endoscopic changes.		'''Lymphocytic colitis''', abbreviated '''LC''', is a type of [[microscopic colitis]]. It has a characteristic clinical presentation and no apparent endoscopic changes.

			''Lymphocytic proctitis'' redirects to here.

	==General==		==General==

Michael: /* Images */

2014-07-05T01:37:35Z

Images

← Older revision		Revision as of 01:37, 5 July 2014
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	Image: Lymphocytic colitis - hps - high mag.jpg \| LC - HPS - high mag. (WC)		Image: Lymphocytic colitis - hps - high mag.jpg \| LC - HPS - high mag. (WC)
	Image: Lymphocytic colitis - hps - very high mag.jpg \| LC - HPS - very high mag. (WC)		Image: Lymphocytic colitis - hps - very high mag.jpg \| LC - HPS - very high mag. (WC)
			</gallery>
			<gallery>
			Image: Lymphocytic proctitis -- low mag.jpg \| LP - low mag.
			Image: Lymphocytic proctitis -- intermed mag.jpg \| LP - intermed. mag.
			Image: Lymphocytic proctitis -- high mag.jpg \| LP - high mag.
			Image: Lymphocytic proctitis -- very high mag.jpg \| LP - very high mag.
	</gallery>		</gallery>
	www:		www:

Michael: /* General */

2014-07-05T01:23:33Z

General

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	*Clinical DDx includes [[irritable bowel syndrome]] - which has no or subtle histopathologic changes.		*Clinical DDx includes [[irritable bowel syndrome]] - which has no or subtle histopathologic changes.
	*This pathology also afflicits rectum; however, it is less commonly found there.		*This pathology also afflicits rectum; however, it is less commonly found there.
	**~~Rectum~~ is afflicted in approximately in 65% of cases.<ref name=pmid12018911>{{cite journal \|author=Agnarsdottir M, Gunnlaugsson O, Orvar KB, ''et al.'' \|title=Collagenous and lymphocytic colitis in Iceland \|journal=Dig. Dis. Sci. \|volume=47 \|issue=5 \|pages=1122–8 \|year=2002 \|month=May \|pmid=12018911 \|doi= \|url=}}</ref>		**The rectum is afflicted in approximately in 65% of cases.<ref name=pmid12018911>{{cite journal \|author=Agnarsdottir M, Gunnlaugsson O, Orvar KB, ''et al.'' \|title=Collagenous and lymphocytic colitis in Iceland \|journal=Dig. Dis. Sci. \|volume=47 \|issue=5 \|pages=1122–8 \|year=2002 \|month=May \|pmid=12018911 \|doi= \|url=}}</ref>

	===Epidemiology===		===Epidemiology===

Michael at 01:22, 5 July 2014

2014-07-05T01:22:59Z

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	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing =
	\| Site = [[colon]]		\| Site = [[colon]], [[rectum]]
	\| Assdx = autoimmune diseases ([[celiac disease]], [[diabetes mellitus]], [[thyroid]] disorders, [[arthritis]])		\| Assdx = autoimmune diseases ([[celiac disease]], [[diabetes mellitus]], [[thyroid]] disorders, [[arthritis]])
	\| Syndromes =		\| Syndromes =
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	Notes:		Notes:
	*Clinical DDx includes [[irritable bowel syndrome]] - which has no or subtle histopathologic changes.		*Clinical DDx includes [[irritable bowel syndrome]] - which has no or subtle histopathologic changes.
			*This pathology also afflicits rectum; however, it is less commonly found there.
			**Rectum is afflicted in approximately in 65% of cases.<ref name=pmid12018911>{{cite journal \|author=Agnarsdottir M, Gunnlaugsson O, Orvar KB, ''et al.'' \|title=Collagenous and lymphocytic colitis in Iceland \|journal=Dig. Dis. Sci. \|volume=47 \|issue=5 \|pages=1122–8 \|year=2002 \|month=May \|pmid=12018911 \|doi= \|url=}}</ref>

	===Epidemiology===		===Epidemiology===

Michael: /* Sign out */

2014-01-13T19:12:33Z

Sign out

← Older revision		Revision as of 19:12, 13 January 2014
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	ASCENDING COLON, BIOPSY:		ASCENDING COLON, BIOPSY:
	- LYMPHOCYTIC COLITIS.		- LYMPHOCYTIC COLITIS.
			</pre>

			<pre>
			RECTUM, BIOPSY:
			- LYMPHOCYTIC PROCTITIS.
			- NEGATIVE FOR ARCHITECTURAL DISTORTION AND NEGATIVE FOR CRYPTITIS.
			- NEGATIVE FOR DYSPLASIA.
	</pre>		</pre>

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	There are no granulomas. No neutrophilic cryptitis is apparent. The epithelium matures		There are no granulomas. No neutrophilic cryptitis is apparent. The epithelium matures
	appropriately to the surface.		appropriately to the surface.

			====Alternate====
			<pre>
			The sections show rectal mucosa with increased intraepithelial lymphocytes (25-30/100
			epithelial cells), apoptotic epithelial cells, abundant lamina propria plasma
			cells, rare lymphoid aggregates and a mild increase of eosinophils (25/1 HPF (0.24
			mm*mm)). There is surface goblet cell depletion. The collagen table is not apparently thickened.

			There is no apparent cryptitis. The architecture is within normal limits.

			</pre>

	==See also==		==See also==

Michael: more

2013-09-30T13:09:52Z

← Older revision		Revision as of 13:09, 30 September 2013
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	\| Micro = intraepithelial lymphocytes (>20/100 enterocytes), none or rare [[PMN]]s, no architectural distortion, normal subepithelial collagen band (< 10 micrometres thick)		\| Micro = intraepithelial lymphocytes (>20/100 enterocytes), none or rare [[PMN]]s, no architectural distortion, normal subepithelial collagen band (< 10 micrometres thick)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[collagenous colitis]], [[infectious colitis]]		\| LMDDx = [[collagenous colitis]], [[infectious colitis]], [[Crohn's disease]] (rare)
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

← Older revision		Revision as of 04:34, 19 March 2016
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	*[[Colon]].		*[[Colon]].
	*[[Collagenous colitis]].		*[[Collagenous colitis]].
			*[[Lymphocytic gastritis]].

	==References==		==References==