Carcinosarcoma - Revision history

Michael at 05:42, 5 August 2015

2015-08-05T05:42:12Z

← Older revision		Revision as of 05:42, 5 August 2015
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			[[Image:Carcinosarcoma - high mag.jpg\|thumb\|right\|Micrograph showing a carcinosarcoma. [[H&E stain]].]]
	'''Carcinosarcoma''' is a tumour with a malignant epithelial component ([[carcinoma]]) and a malignant mesenchymal component ([[sarcoma]]), based on the histomorphology.		'''Carcinosarcoma''' is a tumour with a malignant epithelial component ([[carcinoma]]) and a malignant mesenchymal component ([[sarcoma]]), based on the histomorphology.

Michael: /* Relation to carcinosarcoma, metaplastic carcinoma and sarcomatoid carcinoma */

2015-07-18T03:33:18Z

Relation to carcinosarcoma, metaplastic carcinoma and sarcomatoid carcinoma

← Older revision		Revision as of 03:33, 18 July 2015
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	*Fallopian tube carcinosarcoma.		*Fallopian tube carcinosarcoma.

	==Relation to ~~carcinosarcoma,~~ metaplastic carcinoma and sarcomatoid carcinoma==		==Relation of carcinosarcoma to metaplastic carcinoma and sarcomatoid carcinoma==
	''Carcinosarcoma'' implies that the tumour arose from mesenchymal cells and epithelial cells simultaneously.		''Carcinosarcoma'' implies that the tumour arose from mesenchymal cells and epithelial cells simultaneously.

Michael: tweak

2015-07-17T22:38:10Z

tweak

← Older revision		Revision as of 22:38, 17 July 2015
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	# [[Metaplastic carcinoma]] - implies the tumour arose from epithelial cells that had undergone a (morphologic) transformation (metaplasia).		# [[Metaplastic carcinoma]] - implies the tumour arose from epithelial cells that had undergone a (morphologic) transformation (metaplasia).

	Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s.<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> They typically metastasize as [[carcinoma]]s,<ref name=pmid21309261>{{Cite journal \| last1 = Lopez-Garcia \| first1 = MA. \| last2 = Palacios \| first2 = J. \| title = Pathologic and molecular features of uterine carcinosarcomas. \| journal = Semin Diagn Pathol \| volume = 27 \| issue = 4 \| pages = 274-86 \| month = Nov \| year = 2010 \| doi = \| PMID = 21309261 }}</ref>		Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s.<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> They typically metastasize as [[carcinoma]]s,<ref name=pmid21309261>{{Cite journal \| last1 = Lopez-Garcia \| first1 = MA. \| last2 = Palacios \| first2 = J. \| title = Pathologic and molecular features of uterine carcinosarcomas. \| journal = Semin Diagn Pathol \| volume = 27 \| issue = 4 \| pages = 274-86 \| month = Nov \| year = 2010 \| doi = \| PMID = 21309261 }}</ref> and putatively arise from epithelial cells (only).
	and putatively arise from epithelial cells (only).

	The term ''carcinosarcoma'' is from the morphologic era of pathology;{{fact}} it precedes the modern battery of molecular tests and [[immunohistochemistry]].		The term ''carcinosarcoma'' is from the morphologic era of pathology;{{fact}} it precedes the modern battery of molecular tests and [[immunohistochemistry]].

Michael: +ref

2015-07-17T22:35:56Z

+ref

← Older revision		Revision as of 22:35, 17 July 2015
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	*[[Sarcomatoid carcinoma]].		*[[Sarcomatoid carcinoma]].
	*[[Metaplastic carcinoma]].		*[[Metaplastic carcinoma]].

			==References==
			{{Reflist\|2}}

	{{disambiguation}}		{{disambiguation}}

	[[Category:Gynecologic pathology]]		[[Category:Gynecologic pathology]]

Michael at 22:34, 17 July 2015

2015-07-17T22:34:57Z

← Older revision		Revision as of 22:34, 17 July 2015
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	'''Carcinosarcoma''' is a tumour with a malignant epithelial component ([[carcinoma]]) and a malignant mesenchymal component ([[sarcoma]]), based on histomorphology.		'''Carcinosarcoma''' is a tumour with a malignant epithelial component ([[carcinoma]]) and a malignant mesenchymal component ([[sarcoma]]), based on the histomorphology.

	They can arise in a number of sites:		They can arise in a number of sites:

Michael: /* Relation to carcinosarcoma, metaplastic carcinoma and sarcomatoid carcinoma */

2015-07-17T22:34:19Z

Relation to carcinosarcoma, metaplastic carcinoma and sarcomatoid carcinoma

← Older revision		Revision as of 22:34, 17 July 2015
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	# [[Metaplastic carcinoma]] - implies the tumour arose from epithelial cells that had undergone a (morphologic) transformation (metaplasia).		# [[Metaplastic carcinoma]] - implies the tumour arose from epithelial cells that had undergone a (morphologic) transformation (metaplasia).

	Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s;<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> ~~they~~ putatively arise from epithelial cells (only).		Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s.<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> They typically metastasize as [[carcinoma]]s,<ref name=pmid21309261>{{Cite journal \| last1 = Lopez-Garcia \| first1 = MA. \| last2 = Palacios \| first2 = J. \| title = Pathologic and molecular features of uterine carcinosarcomas. \| journal = Semin Diagn Pathol \| volume = 27 \| issue = 4 \| pages = 274-86 \| month = Nov \| year = 2010 \| doi = \| PMID = 21309261 }}</ref>
			and putatively arise from epithelial cells (only).

	The term ''carcinosarcoma'' is from the morphologic era of pathology;{{fact}} it precedes the modern battery of molecular tests and [[immunohistochemistry]].		The term ''carcinosarcoma'' is from the morphologic era of pathology;{{fact}} it precedes the modern battery of molecular tests and [[immunohistochemistry]].

Michael at 22:32, 17 July 2015

2015-07-17T22:32:02Z

← Older revision		Revision as of 22:32, 17 July 2015
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	*Fallopian tube carcinosarcoma.		*Fallopian tube carcinosarcoma.

	==Relation to ~~carcinoma~~, metaplastic carcinoma and sarcomatoid carcinoma==		==Relation to carcinosarcoma, metaplastic carcinoma and sarcomatoid carcinoma==
	''Carcinosarcoma'' implies that the tumour arose from mesenchymal cells and epithelial cells simultaneously.		''Carcinosarcoma'' implies that the tumour arose from mesenchymal cells and epithelial cells simultaneously.

	This is in contradistinction to ~~(1) ''~~[[~~sarcomatoid~~ carcinoma]]~~s'' which arise~~ from epithelial cells and ~~then transform to become~~ sarcoma-like, and ~~(2) ''~~[[~~metaplastic~~ carcinoma]]~~s'' which arise~~ from epithelial cells that ~~have~~ undergone a (morphologic) transformation (metaplasia).		This is in contradistinction to:
			# [[Sarcomatoid carcinoma]] - implies the tumour arose from epithelial cells only and is sarcoma-like (morphologically), and
			# [[Metaplastic carcinoma]] - implies the tumour arose from epithelial cells that had undergone a (morphologic) transformation (metaplasia).

	Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s;<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> they putatively arise from epithelial cells (only).		Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s;<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> they putatively arise from epithelial cells (only).

			The term ''carcinosarcoma'' is from the morphologic era of pathology;{{fact}} it precedes the modern battery of molecular tests and [[immunohistochemistry]].

	==See also==		==See also==

Michael at 22:21, 17 July 2015

2015-07-17T22:21:17Z

← Older revision		Revision as of 22:21, 17 July 2015
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	*Ovarian carcinosarcoma.		*Ovarian carcinosarcoma.
	*Fallopian tube carcinosarcoma.		*Fallopian tube carcinosarcoma.

			==Relation to carcinoma, metaplastic carcinoma and sarcomatoid carcinoma==
			''Carcinosarcoma'' implies that the tumour arose from mesenchymal cells and epithelial cells simultaneously.

			This is in contradistinction to (1) ''[[sarcomatoid carcinoma]]s'' which arise from epithelial cells and then transform to become sarcoma-like, and (2) ''[[metaplastic carcinoma]]s'' which arise from epithelial cells that have undergone a (morphologic) transformation (metaplasia).

			Uterine carcinosarcomas are generally considered [[metaplastic carcinoma]]s;<ref name=pmid25805398>{{Cite journal \| last1 = Cantrell \| first1 = LA. \| last2 = Blank \| first2 = SV. \| last3 = Duska \| first3 = LR. \| title = Uterine carcinosarcoma: A review of the literature. \| journal = Gynecol Oncol \| volume = 137 \| issue = 3 \| pages = 581-588 \| month = Jun \| year = 2015 \| doi = 10.1016/j.ygyno.2015.03.041 \| PMID = 25805398 }}</ref><ref name=pmid25468677>{{Cite journal \| last1 = Artioli \| first1 = G. \| last2 = Wabersich \| first2 = J. \| last3 = Ludwig \| first3 = K. \| last4 = Gardiman \| first4 = MP. \| last5 = Borgato \| first5 = L. \| last6 = Garbin \| first6 = F. \| title = Rare uterine cancer: carcinosarcomas. Review from histology to treatment. \| journal = Crit Rev Oncol Hematol \| volume = 94 \| issue = 1 \| pages = 98-104 \| month = Apr \| year = 2015 \| doi = 10.1016/j.critrevonc.2014.10.013 \| PMID = 25468677 }}</ref> they putatively arise from epithelial cells (only).

	==See also==		==See also==

Michael at 21:49, 17 July 2015

2015-07-17T21:49:42Z

← Older revision		Revision as of 21:49, 17 July 2015
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	'''Carcinosarcoma''' is a tumour with a malignant epithelial and a malignant mesenchymal component, based on histomorphology.		'''Carcinosarcoma''' is a tumour with a malignant epithelial component ([[carcinoma]]) and a malignant mesenchymal component ([[sarcoma]]), based on histomorphology.

	They can arise in a number of sites:		They can arise in a number of sites:
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	==See also==		==See also==
	*[[Adenosarcoma]].		*[[Adenosarcoma]].
			*[[Sarcomatoid carcinoma]].
	*[[Metaplastic carcinoma]].		*[[Metaplastic carcinoma]].

Michael: redirect

2013-04-18T12:39:35Z

redirect

← Older revision		Revision as of 12:39, 18 April 2013
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	==See also==		==See also==
	*[[Adenosarcoma]].		*[[Adenosarcoma]].
			*[[Metaplastic carcinoma]].

	{{disambiguation}}		{{disambiguation}}

	[[Category:Gynecologic pathology]]		[[Category:Gynecologic pathology]]