Carbonic anhydrase 9 - Revision history

Michael: /* Staining */

2019-03-03T04:56:52Z

Staining

← Older revision		Revision as of 04:56, 3 March 2019
Line 18:		Line 18:
	Note:		Note:
	*‡ A paper by Furjelová ''et al.'' found different results.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>		*‡ A paper by Furjelová ''et al.'' found different results.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>

			===Images===
			<gallery>
			Image: Carbonic anhydrase 9 -- intermed mag.jpg \| CA9 - intermed. mag. (WC)
			Image: Carbonic anhydrase 9 - alt -- high mag.jpg \| CA9 - high mag. (WC)
			Image: Carbonic anhydrase 9 -- very high mag.jpg \| CA9 - very high mag. (WC)
			</gallery>

	==See also==		==See also==

Michael: /* Positive */ fix

2017-08-17T15:13:12Z

Positive: fix

← Older revision		Revision as of 15:13, 17 August 2017
Line 7:		Line 7:
	===Positive===		===Positive===
	*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>		*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>
			**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
	**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>

Michael: /* Positive */

2017-08-17T15:12:25Z

Positive

← Older revision		Revision as of 15:12, 17 August 2017
Line 8:		Line 8:
	*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>		*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
			**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>

Michael at 15:03, 15 December 2016

2016-12-15T15:03:41Z

← Older revision		Revision as of 15:03, 15 December 2016
Line 1:		Line 1:
	'''Carbonic anhydrase 9''', abbreviated '''CA9''', is a common [[immunostain]] used in [[genitourinary pathology]].		'''Carbonic anhydrase 9''', abbreviated '''CA9''' and '''CAIX''', is a common [[immunostain]] used in [[genitourinary pathology]].

	==General==		==General==

Michael: /* Negative */

2016-12-15T15:03:11Z

Negative

← Older revision		Revision as of 15:03, 15 December 2016
Line 16:		Line 16:

	Note:		Note:
	*‡ ~~Another~~ paper found different results.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>		*‡ A paper by Furjelová ''et al.'' found different results.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>

	==See also==		==See also==

Michael: /* Negative */

2016-12-15T15:02:34Z

Negative

← Older revision		Revision as of 15:02, 15 December 2016
Line 13:		Line 13:
	*[[Xp11.2 translocation carcinoma]].<ref name=pmid21088149/>		*[[Xp11.2 translocation carcinoma]].<ref name=pmid21088149/>
	*Breast carcinoma.<ref name=pmid24436269>{{Cite journal \| last1 = Luong-Player \| first1 = A. \| last2 = Liu \| first2 = H. \| last3 = Wang \| first3 = HL. \| last4 = Lin \| first4 = F. \| title = Immunohistochemical reevaluation of carbonic anhydrase IX (CA IX) expression in tumors and normal tissues. \| journal = Am J Clin Pathol \| volume = 141 \| issue = 2 \| pages = 219-25 \| month = Feb \| year = 2014 \| doi = 10.1309/AJCPVJDS28KNYZLD \| PMID = 24436269 }}</ref> ‡		*Breast carcinoma.<ref name=pmid24436269>{{Cite journal \| last1 = Luong-Player \| first1 = A. \| last2 = Liu \| first2 = H. \| last3 = Wang \| first3 = HL. \| last4 = Lin \| first4 = F. \| title = Immunohistochemical reevaluation of carbonic anhydrase IX (CA IX) expression in tumors and normal tissues. \| journal = Am J Clin Pathol \| volume = 141 \| issue = 2 \| pages = 219-25 \| month = Feb \| year = 2014 \| doi = 10.1309/AJCPVJDS28KNYZLD \| PMID = 24436269 }}</ref> ‡
			*[[Seminoma]].<ref name=pmid24436269/>

	Note:		Note:

Michael: /* See also */

2016-12-15T15:01:35Z

Michael: /* Staining */

2016-12-15T14:00:08Z

Staining

← Older revision		Revision as of 14:00, 15 December 2016
Line 9:		Line 9:
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>

	~~Note:~~
	*One paper found that:
	**[[Fibroadenoma]] ~29% of cases.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>
	**Breast carcinoma ~62% of cases.<ref name=pmid23816158/>

	===Negative===		===Negative===
	*[[Xp11.2 translocation carcinoma]].<ref name=pmid21088149/>		*[[Xp11.2 translocation carcinoma]].<ref name=pmid21088149/>
			*Breast carcinoma.<ref name=pmid24436269>{{Cite journal \| last1 = Luong-Player \| first1 = A. \| last2 = Liu \| first2 = H. \| last3 = Wang \| first3 = HL. \| last4 = Lin \| first4 = F. \| title = Immunohistochemical reevaluation of carbonic anhydrase IX (CA IX) expression in tumors and normal tissues. \| journal = Am J Clin Pathol \| volume = 141 \| issue = 2 \| pages = 219-25 \| month = Feb \| year = 2014 \| doi = 10.1309/AJCPVJDS28KNYZLD \| PMID = 24436269 }}</ref> ‡

			Note:
			*‡ Another paper found different results.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>

	==See also==		==See also==

Michael: /* Staining */

2016-12-15T13:58:18Z

Staining

← Older revision		Revision as of 13:58, 15 December 2016
Line 9:		Line 9:
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>
	*[[Fibroadenoma]] ~29% of cases.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>
	*Breast carcinoma ~62% of cases.<ref name=pmid23816158/>		Note:
			*One paper found that:
			**[[Fibroadenoma]] ~29% of cases.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>
			**Breast carcinoma ~62% of cases.<ref name=pmid23816158/>

	===Negative===		===Negative===

Michael: /* Positive */ more

2016-12-15T13:53:22Z

Positive: more

← Older revision		Revision as of 13:53, 15 December 2016
Line 9:		Line 9:
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>
			*[[Fibroadenoma]] ~29% of cases.<ref name=pmid23816158>{{Cite journal \| last1 = Furjelová \| first1 = M. \| last2 = Kovalská \| first2 = M. \| last3 = Jurková \| first3 = K. \| last4 = Horáček \| first4 = J. \| last5 = Carbolová \| first5 = T. \| last6 = Adamkov \| first6 = M. \| title = Carbonic anhydrase IX: a promising diagnostic and prognostic biomarker in breast carcinoma. \| journal = Acta Histochem \| volume = 116 \| issue = 1 \| pages = 89-93 \| month = Jan \| year = 2014 \| doi = 10.1016/j.acthis.2013.05.009 \| PMID = 23816158 }}</ref>
			*Breast carcinoma ~62% of cases.<ref name=pmid23816158/>

	===Negative===		===Negative===

← Older revision		Revision as of 15:13, 17 August 2017
Line 7:		Line 7:
	===Positive===		===Positive===
	*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>		*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>
			**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
	**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>

← Older revision		Revision as of 15:12, 17 August 2017
Line 8:		Line 8:
	*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>		*[[Clear cell renal cell carcinoma]].<ref name=pmid21088149>{{Cite journal \| last1 = Genega \| first1 = EM. \| last2 = Ghebremichael \| first2 = M. \| last3 = Najarian \| first3 = R. \| last4 = Fu \| first4 = Y. \| last5 = Wang \| first5 = Y. \| last6 = Argani \| first6 = P. \| last7 = Grisanzio \| first7 = C. \| last8 = Signoretti \| first8 = S. \| title = Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. \| journal = Am J Clin Pathol \| volume = 134 \| issue = 6 \| pages = 873-9 \| month = Dec \| year = 2010 \| doi = 10.1309/AJCPPPR57HNJMSLZ \| PMID = 21088149 }}</ref>
	*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>		*[[Malignant mesothelioma\|Epithelioid mesothelioma]].<ref name=pmid23503645>{{Cite journal \| last1 = Ordóñez \| first1 = NG. \| title = Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma. \| journal = Mod Pathol \| volume = 26 \| issue = 8 \| pages = 1132-43 \| month = Aug \| year = 2013 \| doi = 10.1038/modpathol.2013.34 \| PMID = 23503645 }}</ref>
			**95% +ve with clone NB100-417 and clone M75.<ref name=pmid18300814>{{Cite journal \| last1 = Al-Ahmadie \| first1 = HA. \| last2 = Alden \| first2 = D. \| last3 = Qin \| first3 = LX. \| last4 = Olgac \| first4 = S. \| last5 = Fine \| first5 = SW. \| last6 = Gopalan \| first6 = A. \| last7 = Russo \| first7 = P. \| last8 = Motzer \| first8 = RJ. \| last9 = Reuter \| first9 = VE. \| title = Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 377-82 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181570343 \| PMID = 18300814 }}</ref>
	*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>		*Benign mesothelium.<ref name=pmid24926090>{{Cite journal \| last1 = Ananthanarayanan \| first1 = V. \| last2 = Tretiakova \| first2 = M. \| last3 = Husain \| first3 = AN. \| last4 = Krausz \| first4 = T. \| last5 = Antic \| first5 = T. \| title = Carbonic anhydrase IX (CAIX) does not differentiate between benign and malignant mesothelium. \| journal = Am J Clin Pathol \| volume = 142 \| issue = 1 \| pages = 82-7 \| month = Jul \| year = 2014 \| doi = 10.1309/AJCP8BJ8CJXUEHZD \| PMID = 24926090 }}</ref>

← Older revision		Revision as of 15:01, 15 December 2016
Line 19:		Line 19:
	==See also==		==See also==
	*[[Immunohistochemistry]].		*[[Immunohistochemistry]].
			*[[RCC (immunostain)]].

	==References==		==References==