ABCC2 - Revision history

Michael at 22:59, 18 May 2026

2026-05-18T22:59:55Z

← Older revision		Revision as of 22:59, 18 May 2026
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	==Papillary renal cell carcinoma==		==Papillary renal cell carcinoma==
	ABCC2 staining is predictive of outcome in [[papillary renal cell carcinoma]]~~; when brush~~ border staining ~~is present it~~ is associated with a worse survival.<ref name=pmid37680023>{{cite journal \|authors=Castillo VF, Masoomian M, Trpkov K, Downes M, Brimo F, van der Kwast T, Yousef GM, Zakhary A, Rotondo F, Saad G, Nguyen VN, Kidanewold W, Streutker C, Rowsell C, Hamdani M, Saleeb RM \|title=ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases \|journal=Histopathology \|volume=83 \|issue=6 \|pages=949–958 \|date=December 2023 \|pmid=37680023 \|doi=10.1111/his.15042 \|url=}}</ref>		ABCC2 staining is predictive of outcome in [[papillary renal cell carcinoma]]:
			*Brush border staining is associated with a worse survival.<ref name=pmid37680023>{{cite journal \|authors=Castillo VF, Masoomian M, Trpkov K, Downes M, Brimo F, van der Kwast T, Yousef GM, Zakhary A, Rotondo F, Saad G, Nguyen VN, Kidanewold W, Streutker C, Rowsell C, Hamdani M, Saleeb RM \|title=ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases \|journal=Histopathology \|volume=83 \|issue=6 \|pages=949–958 \|date=December 2023 \|pmid=37680023 \|doi=10.1111/his.15042 \|url=}}</ref>
			*Brush border staining suggests response to immunotherapy.<ref>{{cite journal \|authors=Castillo VF, Zakhary A, Rotondo F, Di Ciano-Oliveira C, Hamdani M, Adona E, van der Kwast T, Trpkov K, Saleeb R \|title=Papillary renal cell carcinoma with high-ABCC2 shows an immune-evasive profile associated with favorable response to immunotherapy \|journal=J Pathol \|volume=268 \|issue=2 \|pages=188–199 \|date=February 2026 \|pmid=41259021 \|doi=10.1002/path.70001 \|url=}}</ref>

Michael at 22:54, 18 May 2026

2026-05-18T22:54:12Z

← Older revision		Revision as of 22:54, 18 May 2026
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	==Papillary renal cell carcinoma==		==Papillary renal cell carcinoma==
	ABCC2 staining is predictive of outcome in [[papillary renal cell carcinoma]].<ref name=pmid37680023>{{cite journal \|authors=Castillo VF, Masoomian M, Trpkov K, Downes M, Brimo F, van der Kwast T, Yousef GM, Zakhary A, Rotondo F, Saad G, Nguyen VN, Kidanewold W, Streutker C, Rowsell C, Hamdani M, Saleeb RM \|title=ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases \|journal=Histopathology \|volume=83 \|issue=6 \|pages=949–958 \|date=December 2023 \|pmid=37680023 \|doi=10.1111/his.15042 \|url=}}</ref>		ABCC2 staining is predictive of outcome in [[papillary renal cell carcinoma]]; when brush border staining is present it is associated with a worse survival.<ref name=pmid37680023>{{cite journal \|authors=Castillo VF, Masoomian M, Trpkov K, Downes M, Brimo F, van der Kwast T, Yousef GM, Zakhary A, Rotondo F, Saad G, Nguyen VN, Kidanewold W, Streutker C, Rowsell C, Hamdani M, Saleeb RM \|title=ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases \|journal=Histopathology \|volume=83 \|issue=6 \|pages=949–958 \|date=December 2023 \|pmid=37680023 \|doi=10.1111/his.15042 \|url=}}</ref>

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2026-05-18T22:52:05Z

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'''ABCC2''' is an [[immunostain]].

==Papillary renal cell carcinoma==
ABCC2 staining is predictive of outcome in [[papillary renal cell carcinoma]].<ref name=pmid37680023>{{cite journal |authors=Castillo VF, Masoomian M, Trpkov K, Downes M, Brimo F, van der Kwast T, Yousef GM, Zakhary A, Rotondo F, Saad G, Nguyen VN, Kidanewold W, Streutker C, Rowsell C, Hamdani M, Saleeb RM |title=ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases |journal=Histopathology |volume=83 |issue=6 |pages=949–958 |date=December 2023 |pmid=37680023 |doi=10.1111/his.15042 |url=}}</ref>

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry]]