Libre Pathology - Recent changes [en]

Signet ring cell-like adenocarcinoma of the prostate

Michael — Mon, 21 Sep 2026 21:07:07 GMT

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	'''Signet ring cell carcinoma of the prostate'''~~, also~~ '''prostatic signet ring cell carcinoma''', ~~is a rare aggressive form~~ of ~~[[prostate cancer]]~~.		'''Signet ring cell-like adenocarcinoma of the prostate''' is a rare aggressive form of [[prostate cancer]].

			It is also known as '''signet ring cell carcinoma of the prostate''' and '''prostatic signet ring cell carcinoma'''.

			The term "signet ring cell-like" is preferred over "signet ring cell", as per the WHO Blue Book of 2022, as the cells are often mucin negative.<ref name=pmid38929494/><ref name=WHOGU2022>{{Ref WHOGU2022\|209}}</ref>

	==General==		==General==

Signet ring cell carcinoma of the prostate

Michael — Mon, 21 Sep 2026 21:01:13 GMT

Michael moved page Signet ring cell carcinoma of the prostate to Signet ring cell-like adenocarcinoma of the prostate preferred name in WHO 5th edition

← Older revision		Revision as of 21:01, 21 September 2026
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	==Microscopic==		==Microscopic==
	Features:		Features:
	*Signet ring cells - ~~see ''[[basics]]'' article~~.		*Signet ring cells.
			**Large cytoplasmic vacuole, peripherical nucleus with a crescent shape.<ref name=pmid38929494>{{cite journal \| authors = Sakalauskaite M, Garnelyte A, Civilka I, Dulskas A, Kincius M, Patasius A \| title = Prostate Adenocarcinoma with Signet-Ring Cells and Features of Mucin: A Clinical Case and Literature Review \| journal = Medicina (Kaunas) \| volume = 60 \| issue = 6 \| date = May 2024 \| pmid = 38929494 \| pmc = 11205309 \| doi = 10.3390/medicina60060877}}</ref>
			*+/-Conventional prostatic carcinoma.

	DDx:		DDx:
	*Acinar adenocarcinoma - Gleason pattern 4 with very small glands.		*Acinar adenocarcinoma - Gleason pattern 4 with very small glands.
			*Metastatic [[signet ring cell carcinoma]].

	===Images===		===Images===
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	==Stains==		==Stains==
	*Alcian blue-PAS stain +ve.		*Alcian blue-PAS stain +ve.
	*[[PAS stain\|PAS]] -- 50% of cases +ve.<ref name=pmid21123640/>		*[[PAS stain\|PAS]] - 50% of cases +ve.<ref name=pmid21123640/>
	*[[Alcian blue stain\|Alcian blue]] -- 44% of cases +ve.<ref name=pmid21123640/>		*[[Alcian blue stain\|Alcian blue]] - 44% of cases +ve.<ref name=pmid21123640/>

			Note:
			*May be mucin stain -ve.

			==IHC==
			*PSAP +ve.<ref name=pmid21123640/>
			*PSA +ve.
			*CEA -ve.

			Note:
			*If prostate stains (PSAP, PSA, NKX3.1) are negative, a GI primary should be excluded. Clinical correlation may be required.

	==See also==		==See also==
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	==References==		==References==
	{{Reflist\|2}}		{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:Prostate carcinoma]]		[[Category:Prostate carcinoma]]

Prostate cancer

Michael — Mon, 21 Sep 2026 20:39:30 GMT

Prostatic signet ring cell carcinoma: split out

@@ Line 691: / Line 691: @@
 ==Prostatic signet ring cell carcinoma==
-{{Main|Signet ring cell carcinoma}}
+{{Main|Prostatic signet ring cell carcinoma}}
 ==Sarcomatoid carcinoma of the prostate==

Signet ring cell carcinoma of the prostate

Michael — Mon, 21 Sep 2026 20:38:59 GMT

← Older revision		Revision as of 20:38, 21 September 2026
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	'''Signet ring cell carcinoma of the prostate''' is a rare aggressive form of [[prostate cancer]].		'''Signet ring cell carcinoma of the prostate''', also '''prostatic signet ring cell carcinoma''', is a rare aggressive form of [[prostate cancer]].

	==General==		==General==

Prostatic signet ring cell carcinoma

Michael — Mon, 21 Sep 2026 20:38:28 GMT

Changed redirect target from Prostate cancer#Prostatic signet ring cell carcinoma to Signet ring cell carcinoma of the prostate

← Older revision		Revision as of 20:38, 21 September 2026
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	#redirect [[~~Prostate_cancer#Prostatic_signet_ring_cell_carcinoma~~]]		#redirect [[Signet ring cell carcinoma of the prostate]]

Signet ring cell carcinoma of the prostate

Michael — Mon, 21 Sep 2026 20:36:57 GMT

@@ Line 1: / Line 1: @@
 '''Signet ring cell carcinoma of the prostate''' is a rare aggressive form of [[prostate cancer]].
 ==See also==
-*[[Prostate Cancer]].
+*[[Prostate cancer]].
 ==References==

Signet ring cell carcinoma of the prostate

Michael — Mon, 21 Sep 2026 20:35:51 GMT

Created page with "'''Signet ring cell carcinoma of the prostate''' is a rare aggressive form of prostate cancer. ==See also== *Prostate Cancer. ==References== {{Reflist|2}} Category:Diagnosis Category:Prostate carcinoma"

New page

'''Signet ring cell carcinoma of the prostate''' is a rare aggressive form of [[prostate cancer]].

==See also==
*[[Prostate Cancer]].

==References==
{{Reflist|2}}

[[Category:Diagnosis]]
[[Category:Prostate carcinoma]]