Difference between revisions of "Medical lung diseases"

Medical lung diseases (view source)

929 bytes removed , 06:04, 23 December 2015

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 ==Pulmonary Langerhans cell histiocytosis==
 *[[AKA]] eosinophilic granuloma of the lung.
-===General===
+{{Main|Pulmonary Langerhans cell histiocytosis}}
-*Associated with smoking.<ref name=Ref_PPP234>{{Ref PPP|234}}</ref>
-*Not associated with systemic diseases of Langerhans cells ([[AKA]] [[Langerhans cell histiocytosis|Hand-Schueller-Christian disease]]).
-Subtypes:<ref name=Ref_PPP234/>
-*Cellular form.
-*Fibrotic form.
-One form usually predominates.
-===Radiology===
-*Upper lung zones.
-===Microscopic===
-Features:<ref name=Ref_PPP237>{{Ref PPP|237}}</ref>
-*Cellular peribronchiolar nodules with:
-**Langerhans cells - '''key feature''':
-***Pale staining nucleus (H&E) with nuclear infolding - "crumpled tissue paper" appearance.
-**+/-Smoker's macrophages (brown pigmented airspace macrophages).
-**+/-Eosinophilia (may be rare) - '''significantly narrow DDx'''.
-**Chronic inflammatory cells (lymphocytes). (???)
-Images:
-*[http://path.upmc.edu/cases/case299.html Pulmonary LCH & adenocarcinoma - several images (upmc.edu)].
-===IHC===
-*Langerhans cells: S100+ and CD1a+.<ref name=Ref_PPP237>{{Ref PPP|237}}</ref>
 =Granulomatous lung disease=