Difference between revisions of "Atypical polypoid adenomyoma of the uterus"
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| LMDDx = [[endometrioid endometrial carcinoma]], [[endometrium with squamous morules]], [[endocervical adenocarcinoma]] | |||
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| Site = [[uterus]] | |||
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| Prevalence = rare | |||
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| Prognosis = benign | |||
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'''Atypical polypoid adenomyoma of the uterus''' is a rare benign lesion of the [[uterus]]. | '''Atypical polypoid adenomyoma of the uterus''' is a rare benign lesion of the [[uterus]]. | ||
It is usually referred to simply as '''atypical polypoid adenomyoma''' (abbreviated '''APA'''). | It is usually referred to simply as '''''atypical polypoid adenomyoma''''' (abbreviated '''APA'''). | ||
==General== | ==General== | ||
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*[[Endometrioid endometrial carcinoma]]. | *[[Endometrioid endometrial carcinoma]]. | ||
*[[Endometrium with squamous morules]] - more common. | *[[Endometrium with squamous morules]] - more common. | ||
*Endocervical adenocarcinoma. | *[[Endocervical adenocarcinoma]]. | ||
===Images=== | ===Images=== |
Revision as of 02:11, 20 March 2014
Atypical polypoid adenomyoma of the uterus | |
---|---|
Diagnosis in short | |
LM DDx | endometrioid endometrial carcinoma, endometrium with squamous morules, endocervical adenocarcinoma |
Site | uterus |
| |
Prevalence | rare |
Prognosis | benign |
Atypical polypoid adenomyoma of the uterus is a rare benign lesion of the uterus.
It is usually referred to simply as atypical polypoid adenomyoma (abbreviated APA).
General
Gross
- Lower uterine segment.
Microscopic
Features:[2]
- Glands with irregular (non-ovoid) shapes.
- Benign smooth muscle around the glands - key feature.
- Morular squamous metaplasia - balls of squamous cells - very common.
- Nuclear atypia (mild).
DDx:
- Endometrioid endometrial carcinoma.
- Endometrium with squamous morules - more common.
- Endocervical adenocarcinoma.
Images
www:
IHC
Features (glandular component):[1]
- AE1/AE3 +ve.
- CK7 +ve.
- ER +ve.
- PR +ve.
Significant negative (glandular component):[1]
- CK20 -ve.
- CEA -ve.
Sign out
ENDOMETRIUM, CURETTAGE: - ATYPICAL POLYPOID ADENOMYOMA. COMMENT: Atypical polypoid adenomyomas are considered to be benign lesions; however, they may persist or recur in up to half of patients.
See also
References
- ↑ 1.0 1.1 1.2 Terada, T. (Oct 2011). "Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases.". Ann Diagn Pathol 15 (5): 338-41. doi:10.1016/j.anndiagpath.2011.03.008. PMID 21684185.
- ↑ 2.0 2.1 Jakus, S.; Edmonds, P.; Dunton, C.; Holland, G. (Jan 2002). "Atypical polypoid adenomyoma mimicking cervical adenocarcinoma.". J Low Genit Tract Dis 6 (1): 33-8. PMID 17050990.