Difference between revisions of "Atypical polypoid adenomyoma of the uterus"

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they may persist or recur in up to half of patients.
they may persist or recur in up to half of patients.
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==See also==
==See also==
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{{Reflist|2}}
{{Reflist|2}}


[[Category:Uterine tumours]]
[[Category:Gynecologic pathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 02:08, 20 March 2014

Atypical polypoid adenomyoma of the uterus is a rare benign lesion of the uterus.

It is usually referred to simply as atypical polypoid adenomyoma (abbreviated APA).

General

  • Very rare.[1]
  • Benign.[2]
  • Reproductive age women.

Gross

  • Lower uterine segment.

Microscopic

Features:[2]

  • Glands with irregular (non-ovoid) shapes.
  • Benign smooth muscle around the glands - key feature.
  • Morular squamous metaplasia - balls of squamous cells - very common.
  • Nuclear atypia (mild).

DDx:

Images

  • APA - intermed. mag. (WC)

  • APA - high mag. (WC)

  • APA - very high mag. (WC)

www:

IHC

Features (glandular component):[1]

  • AE1/AE3 +ve.
  • CK7 +ve.
  • ER +ve.
  • PR +ve.

Significant negative (glandular component):[1]

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ENDOMETRIUM, CURETTAGE:
- ATYPICAL POLYPOID ADENOMYOMA.

COMMENT:
Atypical polypoid adenomyomas are considered to be benign lesions; however, 
they may persist or recur in up to half of patients.

See also

References

  1. ↑ 1.0 1.1 1.2 Terada, T. (Oct 2011). "Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases.". Ann Diagn Pathol 15 (5): 338-41. doi:10.1016/j.anndiagpath.2011.03.008. PMID 21684185.
  2. ↑ 2.0 2.1 Jakus, S.; Edmonds, P.; Dunton, C.; Holland, G. (Jan 2002). "Atypical polypoid adenomyoma mimicking cervical adenocarcinoma.". J Low Genit Tract Dis 6 (1): 33-8. PMID 17050990.
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